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- W2079406676 abstract "Previous researchers have utilized the Obrist method for measurement of rCRB using end-tidal, exhaled air counts to correct for recirculation. Choice of the appropriate end-tidal air point is difficult and requires rapid air sampling (0.3 sec) with concomitant poor statistics. A comparison was made between this end-tidal air sampling method and a simpler-to-use average, expiratory air curve (6 sec sampling) in 9 normal volunteer controls, and in 9 patients with carotid artery stenosis or occlusion. The Obrist deconvolution technique was adopted for use on a Picker 4 gamma camera and MDS computer. A high sensitivity collimator insert with square holes measuring 1.7 cm across and 3.8 cm in depth was used. A one minute combination Xenon-133 inhalation and equilibrium period was followed by 10 minutes of washout. A two component exponential was fitted to the deconvoluted brain curves. For the functional images, a MDS rainbow color translation table was used. Two sequences of 9 point spatial smoothing were tested, one with a single smooth before curve generation and another with 2 smooths after. The new method, using 6 second, average expiratory air sampling and a single 9 point spatial smooth before curve generation, demonstrated areas of decreased flow which corresponded to the angiographic findings and clinical findings in each case and demonstrated them equal to or better than the standard method. By the new method, very few abnormal areas were found in the controls, and decreases in the control patients were almost always less than when using the 0.3 sec air sampling time." @default.
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- W2079406676 date "1984-09-01" @default.
- W2079406676 modified "2023-09-27" @default.
- W2079406676 title "A GAMMA CAMERA METHOD OF MEASURING REGIONAL CEREBRAL BLOOD FLOW (rCBF) BY Xe-133 WASHOUT TECHNIQUE" @default.
- W2079406676 doi "https://doi.org/10.1097/00003072-198409001-00046" @default.
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