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- W2079406853 abstract "The chromosomal organization of the ribosomal RNA gene cluster from Saccharomyces cerevisiae was investigated. 18 S rRNA R-loops were formed with unfractionated high molecular weight DNA crosslinked once per 2.7 × 103 bases with trioxsalen and observed in the electron microscope. Almost all the R-loops were found in very long continuous 9.34 ± 0.18 × 103 base repeating units. In addition, molecules were found at a frequency of one to two per genome equivalent of rDNA where several rRNA genes were linked to long stretches of non-rDNA. These results suggest that rDNA is arranged in a single tandem repetitive cluster of 100 to 140 genes flanked on one or both sides by non-rDNA." @default.
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- W2079406853 date "1980-04-01" @default.
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- W2079406853 title "Organization of the ribosomal RNA gene cluster in the yeast Saccharomyces cerevisiae" @default.
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- W2079406853 doi "https://doi.org/10.1016/0022-2836(80)90063-7" @default.
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