FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079409874> ?p ?o ?g. }

• W2079409874 abstract "Abstract Background Bioactivities of Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) depend on their chemical forms. The present study was to investigate short term effects of triglyceride (TG), ethyl ester (EE), free fatty acid (FFA) and phospholipid (PL) forms of omega-3 fatty acid (FA) on lipid metabolism in mice, fed high fat or low fat diet. Method Male Balb/c mice were fed with 0.7% different Omega-3 fatty acid formulation: DHA bound free fatty acid (DHA-FFA), DHA bound triglyceride (DHA-TG), DHA bound ethyl ester (DHA-EE) and DHA bound phospholipid (DHA-PL) for 1 week, with dietary fat levels at 5% and 22.5%. Serum and hepatic lipid concentrations were analyzed, as well as the fatty acid composition of liver and brain. Result At low fat level, serum total cholesterol (TC) level in mice fed diets with DHA-FFA, DHA-EE and DHA-PL were significantly lower than that in the control group ( P < 0.05). Hepatic TG level decreased significantly in mice fed diets with DHA-TG ( P < 0.05), DHA-EE ( P < 0.05) and DHA-PL ( P < 0.05), while TC level in liver was significantly lower in mice fed diets with TG and EE compared with the control group ( P < 0.05). At high fat level, mice fed diets with DHA-EE and DHA-PL had significantly lower hepatic TC level compared with the control diet ( P < 0.05). Hepatic PL concentration experienced a significant increase in mice fed the diet with PL at high fat level ( P < 0.05). Furthermore, both at low and high fat levels, hepatic DHA level significantly increased and AA level significantly decreased in all forms of DHA groups ( P < 0.05), compared to control groups at two different fat levels, respectively. Additionally, cerebral DHA level in mice fed diets with DHA-FFA, DHA-EE and DHA-PL significantly increased compared with the control at high fat level ( P < 0.05), but no significant differences were observed among dietary treatments for mice fed diets with low fat level. Conclusion The present study suggested that not only total dietary fat content but also the molecular forms of omega-3 fatty acids contributed to lipid metabolism in mice. DHA-PL showed effective bioactivity in decreasing hepatic and serum TC, TG levels and increasing omega-3 concentration in liver and brain." @default.
• W2079409874 created "2016-06-24" @default.
• W2079409874 creator A5019126433 @default.
• W2079409874 creator A5019394354 @default.
• W2079409874 creator A5030689354 @default.
• W2079409874 creator A5045392886 @default.
• W2079409874 creator A5052589066 @default.
• W2079409874 creator A5052844169 @default.
• W2079409874 creator A5058013198 @default.
• W2079409874 creator A5066134560 @default.
• W2079409874 creator A5081643471 @default.
• W2079409874 date "2012-06-07" @default.
• W2079409874 modified "2023-10-10" @default.
• W2079409874 title "Short term effects of different omega-3 fatty acid formulation on lipid metabolism in mice fed high or low fat diet" @default.
• W2079409874 cites W1513897103 @default.
• W2079409874 cites W1606260191 @default.
• W2079409874 cites W1967398549 @default.
• W2079409874 cites W1967578759 @default.
• W2079409874 cites W1969570572 @default.
• W2079409874 cites W1970533492 @default.
• W2079409874 cites W1972379535 @default.
• W2079409874 cites W1976078647 @default.
• W2079409874 cites W1978727574 @default.
• W2079409874 cites W1982278900 @default.
• W2079409874 cites W1985700244 @default.
• W2079409874 cites W1987787002 @default.
• W2079409874 cites W1994202468 @default.
• W2079409874 cites W2016171777 @default.
• W2079409874 cites W2027793359 @default.
• W2079409874 cites W2038678664 @default.
• W2079409874 cites W2051883615 @default.
• W2079409874 cites W2055735036 @default.
• W2079409874 cites W2060357671 @default.
• W2079409874 cites W2076525475 @default.
• W2079409874 cites W2092194376 @default.
• W2079409874 cites W2094954778 @default.
• W2079409874 cites W2105051225 @default.
• W2079409874 cites W2111757144 @default.
• W2079409874 cites W2121565483 @default.
• W2079409874 cites W2128790723 @default.
• W2079409874 cites W2138341709 @default.
• W2079409874 cites W2142849241 @default.
• W2079409874 cites W2144181696 @default.
• W2079409874 cites W2145076716 @default.
• W2079409874 cites W2156968573 @default.
• W2079409874 cites W2168526937 @default.
• W2079409874 cites W2335147581 @default.
• W2079409874 cites W2407236876 @default.
• W2079409874 cites W2088361793 @default.
• W2079409874 doi "https://doi.org/10.1186/1476-511x-11-70" @default.
• W2079409874 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3393618" @default.
• W2079409874 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22676394" @default.
• W2079409874 hasPublicationYear "2012" @default.
• W2079409874 type Work @default.
• W2079409874 sameAs 2079409874 @default.
• W2079409874 citedByCount "55" @default.
• W2079409874 countsByYear W20794098742013 @default.
• W2079409874 countsByYear W20794098742014 @default.
• W2079409874 countsByYear W20794098742015 @default.
• W2079409874 countsByYear W20794098742016 @default.
• W2079409874 countsByYear W20794098742017 @default.
• W2079409874 countsByYear W20794098742018 @default.
• W2079409874 countsByYear W20794098742019 @default.
• W2079409874 countsByYear W20794098742020 @default.
• W2079409874 countsByYear W20794098742021 @default.
• W2079409874 countsByYear W20794098742022 @default.
• W2079409874 countsByYear W20794098742023 @default.
• W2079409874 crossrefType "journal-article" @default.
• W2079409874 hasAuthorship W2079409874A5019126433 @default.
• W2079409874 hasAuthorship W2079409874A5019394354 @default.
• W2079409874 hasAuthorship W2079409874A5030689354 @default.
• W2079409874 hasAuthorship W2079409874A5045392886 @default.
• W2079409874 hasAuthorship W2079409874A5052589066 @default.
• W2079409874 hasAuthorship W2079409874A5052844169 @default.
• W2079409874 hasAuthorship W2079409874A5058013198 @default.
• W2079409874 hasAuthorship W2079409874A5066134560 @default.
• W2079409874 hasAuthorship W2079409874A5081643471 @default.
• W2079409874 hasBestOaLocation W20794098741 @default.
• W2079409874 hasConcept C126322002 @default.
• W2079409874 hasConcept C134018914 @default.
• W2079409874 hasConcept C185592680 @default.
• W2079409874 hasConcept C19038510 @default.
• W2079409874 hasConcept C22894154 @default.
• W2079409874 hasConcept C2776091944 @default.
• W2079409874 hasConcept C2777171753 @default.
• W2079409874 hasConcept C2778163477 @default.
• W2079409874 hasConcept C2778913445 @default.
• W2079409874 hasConcept C2778918659 @default.
• W2079409874 hasConcept C382228 @default.
• W2079409874 hasConcept C41625074 @default.
• W2079409874 hasConcept C4733338 @default.
• W2079409874 hasConcept C543025807 @default.
• W2079409874 hasConcept C55493867 @default.
• W2079409874 hasConcept C71924100 @default.
• W2079409874 hasConcept C86803240 @default.
• W2079409874 hasConceptScore W2079409874C126322002 @default.
• W2079409874 hasConceptScore W2079409874C134018914 @default.
• W2079409874 hasConceptScore W2079409874C185592680 @default.
• W2079409874 hasConceptScore W2079409874C19038510 @default.
• W2079409874 hasConceptScore W2079409874C22894154 @default.

• next