Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079427667> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2079427667 endingPage "1144" @default.
- W2079427667 startingPage "1138" @default.
- W2079427667 abstract "The crystal structure of the cyclic peptide disulfide Boc-Cys-Pro-Aib-Cys-NHMe has been determined by X-ray diffraction. The peptide crystallizes in the space group P212121, with A = 8.646(1), B = 18.462(2), C = 19.678(3)A and Z = 4. The molecules adopt a highly folded compact conformation, stabilized by two intramolecular 4→ 1 hydrogen bonds between the Cys (1) and Pro (2) CO groups and the Cys (4) and methylamide NH groups, respectively. The backbone conformational angles for the peptide lie very close to those expected for a 310 helix. The S-S bridge adopts a right handed twist with a dihedral angle of 82°. The structure illustrates the role of stereochemically constrained residues, in generating novel peptide conformations.Aib, α-aminoisobutyric acid; Z, benzyloxycarbonyl; Boc, t-butyloxycarbonyl; OMe, methyl ester; OBz, benzyl ester; NHMe, N-methylamide; Tosyl, p-toluenesulfonyl." @default.
- W2079427667 created "2016-06-24" @default.
- W2079427667 creator A5026918024 @default.
- W2079427667 creator A5065728901 @default.
- W2079427667 creator A5080581166 @default.
- W2079427667 date "1981-12-01" @default.
- W2079427667 modified "2023-09-27" @default.
- W2079427667 title "Molecular structure of a cyclic tetrapeptide disulfide. A novel 310 helical conformation with an S-S bridge" @default.
- W2079427667 cites W1975832522 @default.
- W2079427667 cites W1985219505 @default.
- W2079427667 cites W1988952372 @default.
- W2079427667 cites W2012774265 @default.
- W2079427667 cites W20132173 @default.
- W2079427667 cites W2031546787 @default.
- W2079427667 cites W2038147123 @default.
- W2079427667 cites W2052772948 @default.
- W2079427667 cites W2089673268 @default.
- W2079427667 cites W2093451970 @default.
- W2079427667 cites W2126828862 @default.
- W2079427667 cites W2166421779 @default.
- W2079427667 cites W2949644648 @default.
- W2079427667 cites W3005258761 @default.
- W2079427667 doi "https://doi.org/10.1016/0006-291x(81)90241-2" @default.
- W2079427667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7332588" @default.
- W2079427667 hasPublicationYear "1981" @default.
- W2079427667 type Work @default.
- W2079427667 sameAs 2079427667 @default.
- W2079427667 citedByCount "12" @default.
- W2079427667 crossrefType "journal-article" @default.
- W2079427667 hasAuthorship W2079427667A5026918024 @default.
- W2079427667 hasAuthorship W2079427667A5065728901 @default.
- W2079427667 hasAuthorship W2079427667A5080581166 @default.
- W2079427667 hasConcept C100776233 @default.
- W2079427667 hasConcept C105702510 @default.
- W2079427667 hasConcept C185592680 @default.
- W2079427667 hasConcept C27256138 @default.
- W2079427667 hasConcept C2779281246 @default.
- W2079427667 hasConcept C2779564779 @default.
- W2079427667 hasConcept C55493867 @default.
- W2079427667 hasConcept C60984968 @default.
- W2079427667 hasConcept C71240020 @default.
- W2079427667 hasConcept C86803240 @default.
- W2079427667 hasConceptScore W2079427667C100776233 @default.
- W2079427667 hasConceptScore W2079427667C105702510 @default.
- W2079427667 hasConceptScore W2079427667C185592680 @default.
- W2079427667 hasConceptScore W2079427667C27256138 @default.
- W2079427667 hasConceptScore W2079427667C2779281246 @default.
- W2079427667 hasConceptScore W2079427667C2779564779 @default.
- W2079427667 hasConceptScore W2079427667C55493867 @default.
- W2079427667 hasConceptScore W2079427667C60984968 @default.
- W2079427667 hasConceptScore W2079427667C71240020 @default.
- W2079427667 hasConceptScore W2079427667C86803240 @default.
- W2079427667 hasIssue "4" @default.
- W2079427667 hasLocation W20794276671 @default.
- W2079427667 hasLocation W20794276672 @default.
- W2079427667 hasOpenAccess W2079427667 @default.
- W2079427667 hasPrimaryLocation W20794276671 @default.
- W2079427667 hasRelatedWork W1963757155 @default.
- W2079427667 hasRelatedWork W1968331213 @default.
- W2079427667 hasRelatedWork W2007778044 @default.
- W2079427667 hasRelatedWork W2008246149 @default.
- W2079427667 hasRelatedWork W2014764992 @default.
- W2079427667 hasRelatedWork W2045394784 @default.
- W2079427667 hasRelatedWork W2079795152 @default.
- W2079427667 hasRelatedWork W2364794409 @default.
- W2079427667 hasRelatedWork W2438190078 @default.
- W2079427667 hasRelatedWork W2805487264 @default.
- W2079427667 hasVolume "103" @default.
- W2079427667 isParatext "false" @default.
- W2079427667 isRetracted "false" @default.
- W2079427667 magId "2079427667" @default.
- W2079427667 workType "article" @default.