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- W2079431376 abstract "Two forms of a member of the POU domain family of transcriptional regulators, highly related to Oct-2, are selectively expressed in terminally differentiating epidermis and hair follicles. One form, referred to as Skn-1i, contains an amino-terminal domain that inhibits DNA binding and can inhibit transactivation by Oct-1. A second form, Skn-1a, contains an alternative amino terminus and serves to activate cytokeratin 10 (K10) gene expression. The pattern of expression of the Skn-1a/i gene products and the effect of the alternative products on the expression of other genes suggest that these factors serve regulatory functions with respect to epidermal development." @default.
- W2079431376 created "2016-06-24" @default.
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- W2079431376 date "1993-04-02" @default.
- W2079431376 modified "2023-09-23" @default.
- W2079431376 title "Skn-1a and Skn-1i: Two Functionally Distinct Oct-2-Related Factors Expressed in Epidermis" @default.
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- W2079431376 doi "https://doi.org/10.1126/science.7682011" @default.
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