FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079439360> ?p ?o ?g. }

• W2079439360 abstract "Myocardial CT perfusion (CTP) imaging is an application that should greatly benefit from spectral CT through the significant reduction of beam hardening (BH) artifacts using mono-energetic (monoE) image reconstructions. We used a prototype spectral detector CT (SDCT) scanner (Philips Healthcare) and developed advanced processing tools (registration, segmentation, and deconvolution-based flow estimation) for quantitative myocardial CTP in a porcine ischemia model with different degrees of coronary occlusion using a balloon catheter. The occlusion severity was adjusted with fractional flow reserve (FFR) measurements. The SDCT scanner is a single source, dual-layer detector system, which allows simultaneous acquisitions of low and high energy projections, hence enabling accurate projection-based material decomposition and effective reduction of BH-artifacts. In addition, the SDCT scanner eliminates partial scan artifacts with fast (0.27s), full gantry rotation acquisitions. We acquired CTP data under different hemodynamic conditions and reconstructed conventional 120kVp images and projection-based monoenergetic (monoE) images for energies ranging from 55keV-to-120keV. We computed and compared myocardial blood flow (MBF) between different reconstructions. With balloon completely deflated (FFR=1), we compared the mean attenuation in a myocardial region of interest before iodine arrival and at peak iodine enhancement in the left ventricle (LV), and we found that monoE images at 70keV effectively minimized the difference in attenuation, due to BH, to less than 1 HU compared to 14 HU with conventional 120kVp images. Flow maps under baseline condition (FFR=1) were more uniform throughout the myocardial wall at 70keV, whereas with 120kVp data about 12% reduction in blood flow was noticed on BH-hypoattenuated areas compared to other myocardial regions. We compared MBF maps at different keVs under an ischemic condition (FFR < 0.7), and we found that flow-contrast-to-noise-ratio (CNRf ) between LAD ischemic and remote healthy territories attains its maximum (2.87 ± 0.7) at 70keV. As energies diverge from 70keV, we noticed a steady decrease in CNRf and an overestimation of mean-MBF. Flow overestimation was also noticed for conventional 120kVp images in different myocardial regions." @default.
• W2079439360 created "2016-06-24" @default.
• W2079439360 creator A5005898060 @default.
• W2079439360 creator A5011834104 @default.
• W2079439360 creator A5016869850 @default.
• W2079439360 creator A5021196481 @default.
• W2079439360 creator A5034527469 @default.
• W2079439360 creator A5038142458 @default.
• W2079439360 creator A5053655315 @default.
• W2079439360 creator A5056910295 @default.
• W2079439360 creator A5059314323 @default.
• W2079439360 date "2015-03-19" @default.
• W2079439360 modified "2023-09-23" @default.
• W2079439360 title "Dynamic myocardial perfusion in a porcine balloon-induced ischemia model using a prototype spectral detector CT" @default.
• W2079439360 cites W1484080302 @default.
• W2079439360 cites W1934789023 @default.
• W2079439360 cites W1970516435 @default.
• W2079439360 cites W1972037630 @default.
• W2079439360 cites W1993711531 @default.
• W2079439360 cites W2000994625 @default.
• W2079439360 cites W2049152314 @default.
• W2079439360 cites W2063567835 @default.
• W2079439360 cites W2067377776 @default.
• W2079439360 cites W2078284051 @default.
• W2079439360 cites W2083321631 @default.
• W2079439360 cites W2092754534 @default.
• W2079439360 cites W2124331477 @default.
• W2079439360 cites W2124752113 @default.
• W2079439360 cites W2149755434 @default.
• W2079439360 cites W2150286687 @default.
• W2079439360 cites W2162678893 @default.
• W2079439360 cites W2168730277 @default.
• W2079439360 cites W2716822650 @default.
• W2079439360 cites W2831308397 @default.
• W2079439360 cites W4211191293 @default.
• W2079439360 cites W4292172722 @default.
• W2079439360 cites W51616355 @default.
• W2079439360 doi "https://doi.org/10.1117/12.2081547" @default.
• W2079439360 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6961835" @default.
• W2079439360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31942087" @default.
• W2079439360 hasPublicationYear "2015" @default.
• W2079439360 type Work @default.
• W2079439360 sameAs 2079439360 @default.
• W2079439360 citedByCount "6" @default.
• W2079439360 countsByYear W20794393602014 @default.
• W2079439360 countsByYear W20794393602015 @default.
• W2079439360 countsByYear W20794393602017 @default.
• W2079439360 countsByYear W20794393602019 @default.
• W2079439360 countsByYear W20794393602020 @default.
• W2079439360 countsByYear W20794393602021 @default.
• W2079439360 crossrefType "proceedings-article" @default.
• W2079439360 hasAuthorship W2079439360A5005898060 @default.
• W2079439360 hasAuthorship W2079439360A5011834104 @default.
• W2079439360 hasAuthorship W2079439360A5016869850 @default.
• W2079439360 hasAuthorship W2079439360A5021196481 @default.
• W2079439360 hasAuthorship W2079439360A5034527469 @default.
• W2079439360 hasAuthorship W2079439360A5038142458 @default.
• W2079439360 hasAuthorship W2079439360A5053655315 @default.
• W2079439360 hasAuthorship W2079439360A5056910295 @default.
• W2079439360 hasAuthorship W2079439360A5059314323 @default.
• W2079439360 hasBestOaLocation W20794393602 @default.
• W2079439360 hasConcept C120665830 @default.
• W2079439360 hasConcept C121332964 @default.
• W2079439360 hasConcept C126838900 @default.
• W2079439360 hasConcept C135691158 @default.
• W2079439360 hasConcept C136229726 @default.
• W2079439360 hasConcept C141379421 @default.
• W2079439360 hasConcept C146957229 @default.
• W2079439360 hasConcept C154945302 @default.
• W2079439360 hasConcept C158846371 @default.
• W2079439360 hasConcept C192562407 @default.
• W2079439360 hasConcept C2779751349 @default.
• W2079439360 hasConcept C2989005 @default.
• W2079439360 hasConcept C41008148 @default.
• W2079439360 hasConcept C71924100 @default.
• W2079439360 hasConcept C94915269 @default.
• W2079439360 hasConceptScore W2079439360C120665830 @default.
• W2079439360 hasConceptScore W2079439360C121332964 @default.
• W2079439360 hasConceptScore W2079439360C126838900 @default.
• W2079439360 hasConceptScore W2079439360C135691158 @default.
• W2079439360 hasConceptScore W2079439360C136229726 @default.
• W2079439360 hasConceptScore W2079439360C141379421 @default.
• W2079439360 hasConceptScore W2079439360C146957229 @default.
• W2079439360 hasConceptScore W2079439360C154945302 @default.
• W2079439360 hasConceptScore W2079439360C158846371 @default.
• W2079439360 hasConceptScore W2079439360C192562407 @default.
• W2079439360 hasConceptScore W2079439360C2779751349 @default.
• W2079439360 hasConceptScore W2079439360C2989005 @default.
• W2079439360 hasConceptScore W2079439360C41008148 @default.
• W2079439360 hasConceptScore W2079439360C71924100 @default.
• W2079439360 hasConceptScore W2079439360C94915269 @default.
• W2079439360 hasLocation W20794393601 @default.
• W2079439360 hasLocation W20794393602 @default.
• W2079439360 hasLocation W20794393603 @default.
• W2079439360 hasLocation W20794393604 @default.
• W2079439360 hasOpenAccess W2079439360 @default.
• W2079439360 hasPrimaryLocation W20794393601 @default.
• W2079439360 hasRelatedWork W1968770722 @default.
• W2079439360 hasRelatedWork W2061676111 @default.
• W2079439360 hasRelatedWork W2102240528 @default.

• next