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- W2079440332 abstract "Recent advances in our understanding of brain function have come from using light to either control or image neuronal activity. Here we describe an approach that combines both techniques: a micromirror array is used to photostimulate populations of presynaptic neurons expressing channelrhodopsin-2, while a red-shifted voltage-sensitive dye allows optical detection of resulting postsynaptic activity. Such technology allowed us to control the activity of cerebellar interneurons while simultaneously recording inhibitory responses in multiple Purkinje neurons, their postsynaptic targets. This approach should substantially accelerate our understanding of information processing by populations of neurons within brain circuits." @default.
- W2079440332 created "2016-06-24" @default.
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- W2079440332 date "2013-01-01" @default.
- W2079440332 modified "2023-10-02" @default.
- W2079440332 title "Probing the function of neuronal populations: Combining micromirror-based optogenetic photostimulation with voltage-sensitive dye imaging" @default.
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- W2079440332 doi "https://doi.org/10.1016/j.neures.2012.11.006" @default.
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