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- W2079444524 endingPage "841" @default.
- W2079444524 startingPage "837" @default.
- W2079444524 abstract "Stress Inside Out In Gram-negative bacteria, the integrity of the outer membrane is crucial for survival and is an important aspect of resistance to antibiotics. The biogenesis of the major components lipopolysaccharide (LPS) and outer-membrane protein (OMP) of the outer membrane begins in the cytoplasmic compartment, involves export across the inner membrane and transport through the periplasm, and finally requires active insertion into the outer membrane by specialized assembly machines. Lima et al. (p. 837 ) supply results for a model in which serious defects in LPS biogenesis also create problems for OMP biogenesis, thereby producing the two signals needed to activate the σ E stress response pathway." @default.
- W2079444524 created "2016-06-24" @default.
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- W2079444524 date "2013-05-17" @default.
- W2079444524 modified "2023-10-17" @default.
- W2079444524 title "Dual Molecular Signals Mediate the Bacterial Response to Outer-Membrane Stress" @default.
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- W2079444524 doi "https://doi.org/10.1126/science.1235358" @default.
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