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• W2079450512 abstract "A Nodulisporium species (designated Ti-13) was isolated as an endophyte from Cassia fistula . The fungus produces a spectrum of volatile organic compounds (VOCs) that includes ethanol, acetaldehyde and 1,8-cineole as major components. Initial observations of the fungal isolate suggested that reversible attenuation of the organism via removal from the host and successive transfers in pure culture resulted in a 50 % decrease in cineole production unrelated to an overall alteration in fungal growth. A compound (CPM 1 ) was obtained from Betula pendula (silver birch) that increases the production of 1,8-cineole by an attenuated Ti-13 strain to its original level, as measured by a novel bioassay method employing a 1,8-cineole-sensitive fungus ( Sclerotinia sclerotiorum ). The host plant produces similar compounds possessing this activity. Bioactivity assays with structurally similar compounds such as ferulic acid and gallic acid suggested that the CPM 1 does not act as a simple precursor to the biosynthesis of 1,8-cineole. NMR spectroscopy and HPLC-ES-MS indicated that the CPM 1 is a para -substituted benzene with alkyl and carboxyl substituents. The VOCs of Ti-13, especially 1,8-cineole, have potential applications in the industrial, fuel and medical fields." @default.
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• W2079450512 date "2014-08-01" @default.
• W2079450512 modified "2023-09-27" @default.
• W2079450512 title "Functionalized para-substituted benzenes as 1,8-cineole production modulators in an endophytic Nodulisporium species" @default.
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• W2079450512 doi "https://doi.org/10.1099/mic.0.079756-0" @default.
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