Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079455114> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2079455114 abstract "Adenosine triphosphate (ATP) has been shown to be an inhibitory or a stimulatory agent for cell growth in various types of cells. Here, we studied the effects of extracellular ATP on two pancreatic cancer cell lines, PK-1 and YAPC established by us. In both cell lines, ATP inhibited cell growth in a time- and dose-dependent manner, whereas the same doses of ATP stimulated DNA synthesis. Flow cytometric analysis of the cells incubated with or without ATP demonstrated the ATP-induced striking increase in cells at S-phase. The same analysis showed also the increase in sub-G0/G1 population in the same analysis and the electrophoretic pattern of DNA showed the occurrence of ATP-induced cell disintegration likely to be apoptosis. We suggest that extracellular ATP is cytotoxic for pancreatic cancer cells because of its induction of cell cycle arrest at S-phase and cell death, possibly apoptosis, overcoming the promotion of the entry into S-phase." @default.
- W2079455114 created "2016-06-24" @default.
- W2079455114 creator A5003200239 @default.
- W2079455114 creator A5011614398 @default.
- W2079455114 creator A5023866057 @default.
- W2079455114 creator A5032860369 @default.
- W2079455114 creator A5045416314 @default.
- W2079455114 creator A5068757939 @default.
- W2079455114 creator A5071512243 @default.
- W2079455114 creator A5083023900 @default.
- W2079455114 creator A5084699233 @default.
- W2079455114 date "2002-01-01" @default.
- W2079455114 modified "2023-09-27" @default.
- W2079455114 title "Cell cycle arrest and the induction of apoptosis in pancreatic cancer cells exposed to adenosine triphosphate in vitro" @default.
- W2079455114 doi "https://doi.org/10.3892/or.9.1.113" @default.
- W2079455114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11748467" @default.
- W2079455114 hasPublicationYear "2002" @default.
- W2079455114 type Work @default.
- W2079455114 sameAs 2079455114 @default.
- W2079455114 citedByCount "7" @default.
- W2079455114 countsByYear W20794551142017 @default.
- W2079455114 countsByYear W20794551142021 @default.
- W2079455114 crossrefType "journal-article" @default.
- W2079455114 hasAuthorship W2079455114A5003200239 @default.
- W2079455114 hasAuthorship W2079455114A5011614398 @default.
- W2079455114 hasAuthorship W2079455114A5023866057 @default.
- W2079455114 hasAuthorship W2079455114A5032860369 @default.
- W2079455114 hasAuthorship W2079455114A5045416314 @default.
- W2079455114 hasAuthorship W2079455114A5068757939 @default.
- W2079455114 hasAuthorship W2079455114A5071512243 @default.
- W2079455114 hasAuthorship W2079455114A5083023900 @default.
- W2079455114 hasAuthorship W2079455114A5084699233 @default.
- W2079455114 hasConcept C121608353 @default.
- W2079455114 hasConcept C1491633281 @default.
- W2079455114 hasConcept C153911025 @default.
- W2079455114 hasConcept C190283241 @default.
- W2079455114 hasConcept C2779564974 @default.
- W2079455114 hasConcept C28406088 @default.
- W2079455114 hasConcept C2908647359 @default.
- W2079455114 hasConcept C29537977 @default.
- W2079455114 hasConcept C54355233 @default.
- W2079455114 hasConcept C55493867 @default.
- W2079455114 hasConcept C62112901 @default.
- W2079455114 hasConcept C71924100 @default.
- W2079455114 hasConcept C81885089 @default.
- W2079455114 hasConcept C86803240 @default.
- W2079455114 hasConcept C95444343 @default.
- W2079455114 hasConcept C96232424 @default.
- W2079455114 hasConcept C99454951 @default.
- W2079455114 hasConceptScore W2079455114C121608353 @default.
- W2079455114 hasConceptScore W2079455114C1491633281 @default.
- W2079455114 hasConceptScore W2079455114C153911025 @default.
- W2079455114 hasConceptScore W2079455114C190283241 @default.
- W2079455114 hasConceptScore W2079455114C2779564974 @default.
- W2079455114 hasConceptScore W2079455114C28406088 @default.
- W2079455114 hasConceptScore W2079455114C2908647359 @default.
- W2079455114 hasConceptScore W2079455114C29537977 @default.
- W2079455114 hasConceptScore W2079455114C54355233 @default.
- W2079455114 hasConceptScore W2079455114C55493867 @default.
- W2079455114 hasConceptScore W2079455114C62112901 @default.
- W2079455114 hasConceptScore W2079455114C71924100 @default.
- W2079455114 hasConceptScore W2079455114C81885089 @default.
- W2079455114 hasConceptScore W2079455114C86803240 @default.
- W2079455114 hasConceptScore W2079455114C95444343 @default.
- W2079455114 hasConceptScore W2079455114C96232424 @default.
- W2079455114 hasConceptScore W2079455114C99454951 @default.
- W2079455114 hasLocation W20794551141 @default.
- W2079455114 hasLocation W20794551142 @default.
- W2079455114 hasOpenAccess W2079455114 @default.
- W2079455114 hasPrimaryLocation W20794551141 @default.
- W2079455114 hasRelatedWork W1488759898 @default.
- W2079455114 hasRelatedWork W1967057358 @default.
- W2079455114 hasRelatedWork W1977629321 @default.
- W2079455114 hasRelatedWork W2017720960 @default.
- W2079455114 hasRelatedWork W2031272828 @default.
- W2079455114 hasRelatedWork W2032563418 @default.
- W2079455114 hasRelatedWork W2046045750 @default.
- W2079455114 hasRelatedWork W2058888886 @default.
- W2079455114 hasRelatedWork W2063114770 @default.
- W2079455114 hasRelatedWork W2076799900 @default.
- W2079455114 hasRelatedWork W2077305243 @default.
- W2079455114 hasRelatedWork W2080557682 @default.
- W2079455114 hasRelatedWork W2125020378 @default.
- W2079455114 hasRelatedWork W2129688549 @default.
- W2079455114 hasRelatedWork W2151194733 @default.
- W2079455114 hasRelatedWork W2160380481 @default.
- W2079455114 hasRelatedWork W2395841715 @default.
- W2079455114 hasRelatedWork W2398578332 @default.
- W2079455114 hasRelatedWork W2408537173 @default.
- W2079455114 hasRelatedWork W2461359555 @default.
- W2079455114 isParatext "false" @default.
- W2079455114 isRetracted "false" @default.
- W2079455114 magId "2079455114" @default.
- W2079455114 workType "article" @default.