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- W2079469850 abstract "A pyrolytic carbon coating was applied to F-75 chromium-cobalt-molybdenum alloy in an effort to reduce the release of corrosion products in vivo. After intramuscular implantation in the rat, a complex pattern of serum and urine concentration elevations of chromium, cobalt, and nickel was seen. The carbon-coated implants released more chromium and cobalt than uncoated controls, as seen by significantly elevated metal concentrations in serum and urine. Animals receiving carbon-coated implants showed a high rate of recurrent implant site inflammation. Neoplastic infiltration of the implant site occurred in 3 out of 24 animals with coated implants, but not in any of the 16 animals which received either uncoated F-75 microsphere or poly(ethylene) particulate implants." @default.
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- W2079469850 date "1987-10-01" @default.
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- W2079469850 title "Release of corrosion products by F-75 cobalt base alloy in the rat. III: Effects of a carbon surface coating" @default.
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- W2079469850 doi "https://doi.org/10.1002/jbm.820211005" @default.
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