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- W2079476695 abstract "Historically, fungal multigene phylogenies have been reconstructed based on a small number of commonly used genes. The availability of complete fungal genomes has given rise to a new wave of model organisms that provide large number of genes potentially useful for building robust gene genealogies. Unfortunately, cross-utilization of these resources to study phylogenetic relationships in the vast majority of non-model fungi (i.e. orphan species) remains an unexamined question. To address this problem, we developed a method coupled with a program named PHYLORPH (PHYLogenetic markers for ORPHans). The method screens fungal genomic databases (107 fungal genomes fully sequenced) for single copy genes that might be easily transferable and well suited for studies at low taxonomic levels (for example, in species complexes) in non-model fungal species. To maximize the chance to target genes with informative regions, PHYLORPH displays a graphical evaluation system based on the estimation of nucleotide divergence relative to substitution type. The usefulness of this approach was tested by developing markers in four non-model groups of fungal pathogens. For each pathogen considered, 7 to 40% of the 10-15 best candidate genes proposed by PHYLORPH yielded sequencing success. Levels of polymorphism of these genes were compared with those obtained for some genes traditionally used to build fungal phylogenies (e.g. nuclear rDNA, β-tubulin, γ-actin, Elongation factor EF-1α). These genes were ranked among the best-performing ones and resolved accurately taxa relationships in each of the four non-model groups of fungi considered. We envision that PHYLORPH will constitute a useful tool for obtaining new and accurate phylogenetic markers to resolve relationships between closely related non-model fungal species." @default.
- W2079476695 created "2016-06-24" @default.
- W2079476695 creator A5002400393 @default.
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- W2079476695 date "2011-04-13" @default.
- W2079476695 modified "2023-09-26" @default.
- W2079476695 title "Finding Single Copy Genes Out of Sequenced Genomes for Multilocus Phylogenetics in Non-Model Fungi" @default.
- W2079476695 cites W1808127049 @default.
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- W2079476695 cites W1848328006 @default.
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- W2079476695 cites W1964422196 @default.
- W2079476695 cites W1968733465 @default.
- W2079476695 cites W1968961501 @default.
- W2079476695 cites W1977027195 @default.
- W2079476695 cites W1983985796 @default.
- W2079476695 cites W1983989618 @default.
- W2079476695 cites W1985366750 @default.
- W2079476695 cites W1989371134 @default.
- W2079476695 cites W1989552417 @default.
- W2079476695 cites W1995226895 @default.
- W2079476695 cites W2000579908 @default.
- W2079476695 cites W2003001917 @default.
- W2079476695 cites W2003233049 @default.
- W2079476695 cites W2005746024 @default.
- W2079476695 cites W2012980591 @default.
- W2079476695 cites W2020382384 @default.
- W2079476695 cites W2022224847 @default.
- W2079476695 cites W2024424737 @default.
- W2079476695 cites W2025317241 @default.
- W2079476695 cites W2030773581 @default.
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- W2079476695 cites W2034961232 @default.
- W2079476695 cites W2045017146 @default.
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- W2079476695 cites W2069232043 @default.
- W2079476695 cites W2071467238 @default.
- W2079476695 cites W2074785145 @default.
- W2079476695 cites W2080917359 @default.
- W2079476695 cites W2088683017 @default.
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- W2079476695 cites W2096673997 @default.
- W2079476695 cites W2103950304 @default.
- W2079476695 cites W2105764044 @default.
- W2079476695 cites W2112956791 @default.
- W2079476695 cites W2122526845 @default.
- W2079476695 cites W2124166542 @default.
- W2079476695 cites W2124787268 @default.
- W2079476695 cites W2126045294 @default.
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- W2079476695 cites W2127235397 @default.
- W2079476695 cites W2128227962 @default.
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- W2079476695 cites W2131527832 @default.
- W2079476695 cites W2132926880 @default.
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- W2079476695 cites W2143592941 @default.
- W2079476695 cites W2143856099 @default.
- W2079476695 cites W2144084326 @default.
- W2079476695 cites W2144257829 @default.
- W2079476695 cites W2144449666 @default.
- W2079476695 cites W2144456315 @default.
- W2079476695 cites W2144469962 @default.
- W2079476695 cites W2146351150 @default.
- W2079476695 cites W2146984921 @default.
- W2079476695 cites W2150227862 @default.
- W2079476695 cites W2151267776 @default.
- W2079476695 cites W2159184522 @default.
- W2079476695 cites W2159394744 @default.
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- W2079476695 cites W2163373465 @default.
- W2079476695 cites W2178119788 @default.
- W2079476695 cites W4205942999 @default.
- W2079476695 cites W4232765377 @default.
- W2079476695 cites W4241688084 @default.
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- W2079476695 doi "https://doi.org/10.1371/journal.pone.0018803" @default.
- W2079476695 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3076447" @default.
- W2079476695 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21533204" @default.
- W2079476695 hasPublicationYear "2011" @default.
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