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• W2079483060 startingPage "123" @default.
• W2079483060 abstract "In order to test the Thrifty Phenotype Hypothesis on hearing, data from two cross-sectional studies on hearing were re-evaluated. The data sets comprised 500 18-year-old conscripts, and 483 noise-exposed male employees. Sensorineural hearing loss (SNHL) was over-represented among conscripts with a short stature (odds ratio = 2.2) or hearing loss in the family (odds ration = 4.2), but not among noise-exposed conscripts (odds ratio = 0.9–1.3). Among noise-exposed short employees, hypertension and age exhibited a negative impact on high frequency hearing thresholds, while among tall employees hypertension had no effect on hearing and the influence of age was less pronounced (p < 0.01 for body height; p < 0.02 for age, hypertension and the interaction between body height and hypertension; p < 0.05 for the interaction between body height and age). This suggests that mechanisms linked to fetal programming and growth retardation and/or insulin-like growth factor 1 levels during fetal life, such as a delayed cell cycle during the time window when the cochlea develops, may cause SNHL in adulthood." @default.
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• W2079483060 date "2005-07-01" @default.
• W2079483060 modified "2023-10-11" @default.
• W2079483060 title "The association between short stature and sensorineural hearing loss" @default.
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• W2079483060 doi "https://doi.org/10.1016/j.heares.2005.03.019" @default.
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