Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079484785> ?p ?o ?g. }
- W2079484785 endingPage "1743" @default.
- W2079484785 startingPage "1731" @default.
- W2079484785 abstract "Spatial patterns of brain atrophy in mild cognitive impairment (MCI) and Alzheimer's disease (AD) were measured via methods of computational neuroanatomy. These patterns were spatially complex and involved many brain regions. In addition to the hippocampus and the medial temporal lobe gray matter, a number of other regions displayed significant atrophy, including orbitofrontal and medial-prefrontal grey matter, cingulate (mainly posterior), insula, uncus, and temporal lobe white matter. Approximately 2/3 of the MCI group presented patterns of atrophy that overlapped with AD, whereas the remaining 1/3 overlapped with cognitively normal individuals, thereby indicating that some, but not all, MCI patients have significant and extensive brain atrophy in this cohort of MCI patients. Importantly, the group with AD-like patterns presented much higher rate of MMSE decline in follow-up visits; conversely, pattern classification provided relatively high classification accuracy (87%) of the individuals that presented relatively higher MMSE decline within a year from baseline. High-dimensional pattern classification, a nonlinear multivariate analysis, provided measures of structural abnormality that can potentially be useful for individual patient classification, as well as for predicting progression and examining multivariate relationships in group analyses." @default.
- W2079484785 created "2016-06-24" @default.
- W2079484785 creator A5011451324 @default.
- W2079484785 creator A5032267453 @default.
- W2079484785 creator A5033988758 @default.
- W2079484785 creator A5046330622 @default.
- W2079484785 date "2008-02-01" @default.
- W2079484785 modified "2023-09-30" @default.
- W2079484785 title "Spatial patterns of brain atrophy in MCI patients, identified via high-dimensional pattern classification, predict subsequent cognitive decline" @default.
- W2079484785 cites W1476286403 @default.
- W2079484785 cites W156249982 @default.
- W2079484785 cites W1929729372 @default.
- W2079484785 cites W1964038928 @default.
- W2079484785 cites W1970240370 @default.
- W2079484785 cites W1971316923 @default.
- W2079484785 cites W1974471856 @default.
- W2079484785 cites W1979062697 @default.
- W2079484785 cites W1980989370 @default.
- W2079484785 cites W1981190087 @default.
- W2079484785 cites W1989217296 @default.
- W2079484785 cites W1994206031 @default.
- W2079484785 cites W1998710995 @default.
- W2079484785 cites W2000658130 @default.
- W2079484785 cites W2004757203 @default.
- W2079484785 cites W2004908879 @default.
- W2079484785 cites W2006325146 @default.
- W2079484785 cites W2007483873 @default.
- W2079484785 cites W2007804187 @default.
- W2079484785 cites W2008022914 @default.
- W2079484785 cites W2008092392 @default.
- W2079484785 cites W2012076586 @default.
- W2079484785 cites W2012582740 @default.
- W2079484785 cites W2015580059 @default.
- W2079484785 cites W2016813523 @default.
- W2079484785 cites W2019541714 @default.
- W2079484785 cites W2033358375 @default.
- W2079484785 cites W2034742899 @default.
- W2079484785 cites W2040545532 @default.
- W2079484785 cites W2044367669 @default.
- W2079484785 cites W2045867209 @default.
- W2079484785 cites W2050784521 @default.
- W2079484785 cites W2053935454 @default.
- W2079484785 cites W2058292818 @default.
- W2079484785 cites W2058846847 @default.
- W2079484785 cites W2060467098 @default.
- W2079484785 cites W2061204055 @default.
- W2079484785 cites W2067140282 @default.
- W2079484785 cites W2067279300 @default.
- W2079484785 cites W2069476204 @default.
- W2079484785 cites W2084258254 @default.
- W2079484785 cites W2086978209 @default.
- W2079484785 cites W2087763856 @default.
- W2079484785 cites W2092423057 @default.
- W2079484785 cites W2092730500 @default.
- W2079484785 cites W2094325876 @default.
- W2079484785 cites W2107287771 @default.
- W2079484785 cites W2108707886 @default.
- W2079484785 cites W2115424422 @default.
- W2079484785 cites W2120111102 @default.
- W2079484785 cites W2123225824 @default.
- W2079484785 cites W2123261378 @default.
- W2079484785 cites W2124114508 @default.
- W2079484785 cites W2131437398 @default.
- W2079484785 cites W2132131830 @default.
- W2079484785 cites W2132458496 @default.
- W2079484785 cites W2135612359 @default.
- W2079484785 cites W2136579519 @default.
- W2079484785 cites W2139906140 @default.
- W2079484785 cites W2140082297 @default.
- W2079484785 cites W2143615397 @default.
- W2079484785 cites W2143731392 @default.
- W2079484785 cites W2148046162 @default.
- W2079484785 cites W2152839913 @default.
- W2079484785 cites W2159320983 @default.
- W2079484785 cites W2161266529 @default.
- W2079484785 cites W2165278596 @default.
- W2079484785 cites W2166035259 @default.
- W2079484785 cites W2167393047 @default.
- W2079484785 cites W2889574304 @default.
- W2079484785 cites W4241388204 @default.
- W2079484785 cites W4249221250 @default.
- W2079484785 doi "https://doi.org/10.1016/j.neuroimage.2007.10.031" @default.
- W2079484785 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2861339" @default.
- W2079484785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18053747" @default.
- W2079484785 hasPublicationYear "2008" @default.
- W2079484785 type Work @default.
- W2079484785 sameAs 2079484785 @default.
- W2079484785 citedByCount "435" @default.
- W2079484785 countsByYear W20794847852012 @default.
- W2079484785 countsByYear W20794847852013 @default.
- W2079484785 countsByYear W20794847852014 @default.
- W2079484785 countsByYear W20794847852015 @default.
- W2079484785 countsByYear W20794847852016 @default.
- W2079484785 countsByYear W20794847852017 @default.
- W2079484785 countsByYear W20794847852018 @default.
- W2079484785 countsByYear W20794847852019 @default.
- W2079484785 countsByYear W20794847852020 @default.
- W2079484785 countsByYear W20794847852021 @default.