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- W2079491105 abstract "Earlier reports found that calsenilin is a transcriptional repressor or a subunit of plasma membrane channel, and indicated that calsenilin was present in the nucleus or plasma membrane. Immunohistochemical and subcellular fractionation analysis, however, revealed that calsenilin/DREAM/KChIP3 was distributed throughout the cytoplasm of SK-N-BE2(C), Jurkat, and HeLa cells. In addition, the expression of calsenilin suppressed the ATP-induced increase in intracellular Ca2+ concentrations. By increase in intracellular calcium concentration, calsenilin was translocated into the nucleus." @default.
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- W2079491105 date "2008-08-06" @default.
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- W2079491105 title "Characterization of subcellular localization and Ca2+ modulation of calsenilin/DREAM/KChIP3" @default.
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- W2079491105 doi "https://doi.org/10.1097/wnr.0b013e3283089209" @default.
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