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• W2079491632 abstract "Immunohistochemical expression of S-100 protein and its subunits alpha and beta in a total of 27 cases of cystadenolymphomas of the parotid gland is described by means of polyclonal anti-S-100 protein antiserum and monoclonal antibodies against S-100 alpha and beta. Normal salivary glands showed strongly positive staining for S-100 alpha in acinic cells and a negative or slightly positive reaction in ductal cells; however, they were usually negative for S-100 beta staining. Neoplastic epithelial cells of cystadenolymphomas showed slightly positive staining for S-100 alpha in their cytoplasm, and there was a strongly positive reaction in a limited number of tumour cells. The S-100 beta subunit was expressed as a fine granular deposition in the apical cytoplasm of tumour cells. S-100 protein staining with the polyclonal reagent was usually negative or slightly positive in the tumour epithelia, but a small number of strongly positive cells were scattered throughout the tumour epithelia, suggesting the presence of Langerhan's cells. Interdigitating cells in lymphoid tissue reacted positively to monoclonal S-100 alpha as well as to the polyclonal antiserum." @default.
• W2079491632 created "2016-06-24" @default.
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• W2079491632 date "1989-01-01" @default.
• W2079491632 modified "2023-09-24" @default.
• W2079491632 title "Heterogeneous expression of S-100 protein subunits α and β in cystadenolymphomas of salivary glands" @default.
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• W2079491632 doi "https://doi.org/10.1016/s0065-1281(89)80040-6" @default.
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