FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079522024> ?p ?o ?g. }

• W2079522024 endingPage "94" @default.
• W2079522024 startingPage "51" @default.
• W2079522024 abstract "The neuropathological findings in 54 cases of prolonged coma and in various post-comatose transitory stages following closed head injury are reported. They were chosen from a series of 576 necropsies of closed cranio-cerebral injuries showing survival from some minutes up to 1 year. The cases with protracted coma (survival 12–301 days) are compared with a control series of patients showing long survival after short periods of initial coma. In cases of prolonged post-traumatic coma, the brains showed multifocal lesions of primary and secondary traumatic origin often associated with late sequelae of these alterations. Skull fractures, expanding intracranial haemorrhages and cortical contusions were less frequent than in acute fatal cases, whereas the results of mechanical lesions in the basal ganglia, callosum-fornix system and cerebral white matter were comparatively frequent. The morphological picture of this “protracted post-traumatic encephalopathy”, however, is dominated by secondary (reactive) lesions and their sequelae which preferentially account for the clinical course. In addition to severe and often diffuse degeneration of the cerebral white matter of primary and secondary traumatic origin, multiple lesions were recognized in the basal ganglia, corpus callosum, hippocampal gyri, and limbic system. The incidence and extent of these results of various post-traumatic circulatory and anoxic disorders exceeds those of the mechanical lesions. Whereas severe primary damage to the brain stem is not usually survived for longer than a few hours, the most frequent and most conspicuous findings in prolonged coma are secondary lesions of the upper brain stem. They were present in 83.0% of the reported series. They included focal necroses, haemorrhages and their sequelae as well as diffuse glial dystrophies. They are the mechanical and vascular sequelae of increased intracranial pressure and thus closely resemble brain stem lesions which occur in space-occupying processes of varying aetiology. These brain stem lesions show characteristic patterns of distribution which make for close clinical-morphological correlations. They often affect central parts of the rostral brain stem and basal diencephalon involving the rostral mesencephalic activating system. These lesions account for persistent impairment of alertness and conditions consistent with chronic functional decerebrate states. Comparing the clinical data and anatomical findings in the present series of cases showing late sequelae of closed head injury, evidence is presented that brain stem lesions predominantly account for the clinical features and the prognosis of these severe post-traumatic conditions. The associated multiple lesions of the cortex, cerebral white matter and other subcortical regions may merely modify the clinical picture. The pathogenesis, topographical pattern and physiological pathology of the rostral brain stem lesions in these forms of post-traumatic encephalopathy are discussed." @default.
• W2079522024 created "2016-06-24" @default.
• W2079522024 creator A5042083351 @default.
• W2079522024 creator A5057547669 @default.
• W2079522024 date "1970-01-01" @default.
• W2079522024 modified "2023-09-23" @default.
• W2079522024 title "Protracted post-traumatic encephalopathy" @default.
• W2079522024 cites W1975849925 @default.
• W2079522024 cites W1977416667 @default.
• W2079522024 cites W1980236249 @default.
• W2079522024 cites W1982651944 @default.
• W2079522024 cites W1999593475 @default.
• W2079522024 cites W2000309507 @default.
• W2079522024 cites W2004689835 @default.
• W2079522024 cites W2012062176 @default.
• W2079522024 cites W2013773701 @default.
• W2079522024 cites W2015765420 @default.
• W2079522024 cites W2017068097 @default.
• W2079522024 cites W2030722085 @default.
• W2079522024 cites W2034450065 @default.
• W2079522024 cites W2039893835 @default.
• W2079522024 cites W2044930257 @default.
• W2079522024 cites W2044956386 @default.
• W2079522024 cites W2046115770 @default.
• W2079522024 cites W2062649574 @default.
• W2079522024 cites W2066307374 @default.
• W2079522024 cites W2066671411 @default.
• W2079522024 cites W2074160003 @default.
• W2079522024 cites W2074604416 @default.
• W2079522024 cites W2077865370 @default.
• W2079522024 cites W2082330186 @default.
• W2079522024 cites W2124385018 @default.
• W2079522024 cites W2130819883 @default.
• W2079522024 cites W2155416313 @default.
• W2079522024 cites W2169516467 @default.
• W2079522024 cites W2212330024 @default.
• W2079522024 cites W2266157360 @default.
• W2079522024 cites W2286373349 @default.
• W2079522024 cites W2400812001 @default.
• W2079522024 cites W2410263692 @default.
• W2079522024 cites W2413107740 @default.
• W2079522024 cites W2468924307 @default.
• W2079522024 cites W2498445379 @default.
• W2079522024 cites W2885096001 @default.
• W2079522024 cites W2914555501 @default.
• W2079522024 cites W2993905353 @default.
• W2079522024 cites W329022613 @default.
• W2079522024 cites W4294349871 @default.
• W2079522024 cites W4296981296 @default.
• W2079522024 doi "https://doi.org/10.1016/0022-510x(70)90091-2" @default.
• W2079522024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5411990" @default.
• W2079522024 hasPublicationYear "1970" @default.
• W2079522024 type Work @default.
• W2079522024 sameAs 2079522024 @default.
• W2079522024 citedByCount "66" @default.
• W2079522024 countsByYear W20795220242012 @default.
• W2079522024 countsByYear W20795220242013 @default.
• W2079522024 countsByYear W20795220242016 @default.
• W2079522024 countsByYear W20795220242021 @default.
• W2079522024 countsByYear W20795220242023 @default.
• W2079522024 crossrefType "journal-article" @default.
• W2079522024 hasAuthorship W2079522024A5042083351 @default.
• W2079522024 hasAuthorship W2079522024A5057547669 @default.
• W2079522024 hasConcept C118552586 @default.
• W2079522024 hasConcept C190385971 @default.
• W2079522024 hasConcept C2778426673 @default.
• W2079522024 hasConcept C2778621155 @default.
• W2079522024 hasConcept C2911139526 @default.
• W2079522024 hasConcept C3017944768 @default.
• W2079522024 hasConcept C545542383 @default.
• W2079522024 hasConcept C71924100 @default.
• W2079522024 hasConceptScore W2079522024C118552586 @default.
• W2079522024 hasConceptScore W2079522024C190385971 @default.
• W2079522024 hasConceptScore W2079522024C2778426673 @default.
• W2079522024 hasConceptScore W2079522024C2778621155 @default.
• W2079522024 hasConceptScore W2079522024C2911139526 @default.
• W2079522024 hasConceptScore W2079522024C3017944768 @default.
• W2079522024 hasConceptScore W2079522024C545542383 @default.
• W2079522024 hasConceptScore W2079522024C71924100 @default.
• W2079522024 hasIssue "1" @default.
• W2079522024 hasLocation W20795220241 @default.
• W2079522024 hasLocation W20795220242 @default.
• W2079522024 hasOpenAccess W2079522024 @default.
• W2079522024 hasPrimaryLocation W20795220241 @default.
• W2079522024 hasRelatedWork W173150193 @default.
• W2079522024 hasRelatedWork W2554033142 @default.
• W2079522024 hasRelatedWork W2782409382 @default.
• W2079522024 hasRelatedWork W2925148972 @default.
• W2079522024 hasRelatedWork W2964868669 @default.
• W2079522024 hasRelatedWork W3005450229 @default.
• W2079522024 hasRelatedWork W3180375355 @default.
• W2079522024 hasRelatedWork W4206130301 @default.
• W2079522024 hasRelatedWork W4206345186 @default.
• W2079522024 hasRelatedWork W4237759292 @default.
• W2079522024 hasVolume "10" @default.
• W2079522024 isParatext "false" @default.
• W2079522024 isRetracted "false" @default.
• W2079522024 magId "2079522024" @default.

• next