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• W2079522905 abstract "As determined by light microscopic autoradiography, parts of the nervous system of Phocanema decipiens have selective and high affinity mechanisms for the uptake of tritiated noradrenaline, dihydroxyphenylalanine (dopa) and 5-hydroxytryptamine. In the nervous system, noradrenaline is accumulated only by the four papillary nerves and two fibers in the nerve ring. The precursor dopa is also taken up by these neurons and, in addition, by the lateral nerves. 5-Hydroxytryptamime is accumulated by the three pharyngeal nerves, two cells in each lateral ganglion, and two other fibers in the nerve ring. With adjacent ultrathin sections, the labelled papillary nerve and lateral ganglion were examined ultrastructurally and found to contain various dense core vesicles which are similar to those in other aminergic neurons. The adjoining unlabelled cells of the same neurons are found, on the other hand, to contain dense agranular vesicles. With these results, the noradrenaline accumulating neurons are suggested to be noradrenergic and to contain the amine synthesizing enzymes. The lateral nerves are regarded, for the present, as dopaminergic neurons. These suggestions are in agreement with the previous demonstration of catecholaminergic neurons in this nematode. The 5-hydroxytryptamine accumulating neurons are tentatively identified as tryptaminergic." @default.
• W2079522905 created "2016-06-24" @default.
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• W2079522905 date "1976-01-01" @default.
• W2079522905 modified "2023-09-26" @default.
• W2079522905 title "Selective uptake of noradrenaline, dopa, and 5-Hydroxytryptamine by the nervous system of Phocanema decipiens (Nematoda): A light autoradiographic and ultrastructural study" @default.
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• W2079522905 doi "https://doi.org/10.1016/0040-8166(76)90003-3" @default.
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