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- W2079532393 abstract "Koudela B. and Vitovec J. 1992. Biology and pathogenicity of Eimeria spinosa Henry, 1931 in experimentally infected pigs. International Journal for Parasitology22: 651–656. A single-species isolate of E. spinosa from a diarrheic weaned pig was used to determine the endogenous development and pathogenicity of this swine coccidium. Seven out of 14 inoculated pigs developed endogenous stages or passed oocysts of E. spinosa in their feces. Immunosuppressive treatment with cyclophosphamide had no effect on the susceptibility to infection with E. spinosa in young pigs. The endogenous stages developed within the apical cytoplasm of the enterocytes lining the distal part of the villi in the posterior jejunum. The asexual development comprised three generations of meronts, which were seen at 5, 7 and 9 days postinfection (DPI). Meronts of the first generation measured 6–8 μm and produced 10–14 merozoites 4–6 μm in length. The second generation of meronts measured 6–8 μm and contained 10–20 merozoites 4–6 μm in length. Third generation mature meronts (8–10 μm) on DPI 9 contained 12–20 merozoites measuring 5–7 μm, which were more crescent-shaped and less blunt than the merozoites at 5 and 7 DPI. Merogony continued after formation of the gametes and the first fully developed macrogametes (10–14 μm), microgametes (9–12 μm), and oocysts were also seen at 9 DPI. The prepatent period was 8 or 9 days, but the patent period was not determined. In the present study E. spinosa infection did not produce overt clinical signs. Pathological changes consisted of an inflammatory infiltration in the lamina propria of the posterior jejunum, Peyer's patches activation and sporadic erosions scattered at the villous tips. No villous atrophy in association with a large number of endogenous stages was observed." @default.
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- W2079532393 date "1992-08-01" @default.
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- W2079532393 title "Biology and pathogenicity of Eimeria spinosa Henry, 1931 in experimentally infected pigs" @default.
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- W2079532393 doi "https://doi.org/10.1016/0020-7519(92)90014-c" @default.
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