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- W2079532922 abstract "ABSTRACT Among 17 HLA-A2-positive healthy adults, CD8 + T-cell responses against an HLA-A2-restricted matrix protein 1 (M1) epitope increased after immunization with trivalent inactivated influenza vaccine (TIV) in two individuals. The presence of M1 in TIV was confirmed by Western blotting. T-cell cytotoxicity assays showed that TIV is processed and the epitope is presented by antigen-presenting cells to an M1 epitope-specific CD8 + T-cell line for specific lysis. These data show that TIV, which is formulated to contain surface glycoproteins to induce serotype-specific antibody responses, also contains M1, capable of inducing subtype cross-reactive CD8 + T-cell responses in some vaccinees." @default.
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- W2079532922 date "2008-09-15" @default.
- W2079532922 modified "2023-10-17" @default.
- W2079532922 title "Influenza A Virus Matrix Protein 1-Specific Human CD8<sup>+</sup>T-Cell Response Induced in Trivalent Inactivated Vaccine Recipients" @default.
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- W2079532922 doi "https://doi.org/10.1128/jvi.01047-08" @default.
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