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• W2079554499 abstract "Yttrium binding ligands DOTA, caDTPA and CT-DTPA were each conjugated to monoclonal antibody B72.3, labelled with 90Y and injected into mice in order to assess the in vivo inertness of the antibody-linked 90Y-ligand complexes. Levels of 90Y in femur shafts of the DOTA-B72.3 mice were low, being ~ 7 and 44%, respectively, of levels in the femur shafts of the caDTPA-B72.3 and CT-DTPA-B72.3 treated mice. This finding demonstrates the greater inertness and by implication the greater suitability for immunotherapy of the DOTA-90Y complex." @default.
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• W2079554499 date "1991-01-01" @default.
• W2079554499 modified "2023-09-27" @default.
• W2079554499 title "The in vivo release of 90Y from cyclic and acyclic ligand-antibody conjugates" @default.
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• W2079554499 doi "https://doi.org/10.1016/0883-2897(91)90107-v" @default.
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