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• W2079558846 endingPage "e63229" @default.
• W2079558846 startingPage "e63229" @default.
• W2079558846 abstract "To investigate refractive and axial responses to the shift of focal plane resulting from the interchange of two monochromatic lights separately corresponding to the peak wavelengths of the cones absorption spectrum in retina, fifty 2-week-old pigmented guinea pigs were randomly assigned to five groups based on the mode of illumination: short-wavelength light (SL), middle-wavelength light (ML) and broad-band white light (BL) for 20 weeks, SL for 10 weeks followed by ML for 10 weeks (STM), as well as ML for 10 weeks followed by SL for 10 weeks (MTS). Biometric and refractive measurements were then performed every 2 weeks. After 10 weeks, SL and STM groups became more hyperopic and had less vitreous elongation than BL group. However, ML and MTS groups became more myopic and had more vitreous elongation. After interchange of the monochromatic light, the refractive error decreased rapidly by about 1.93D and the vitreous length increased by 0.14 mm in STM group from 10 to 12 weeks. After that, there were no significant intergroup differences between STM and BL groups. The interchange from ML to SL quickly increased the refractive error by about 1.53D and decreased the vitreous length by about 0.13 mm in MTS group after two weeks. At this time, there were also no significant intergroup differences between MTS and BL groups. The guinea pig eye can accurately detect the shift in focal plane caused by interchange of two monochromatic lights and rapidly generate refractive and axial responses. However, an excessive compensation was induced. Some properties of photoreceptors or retina may be changed by the monochromatic light to influence the following refractive development." @default.
• W2079558846 created "2016-06-24" @default.
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• W2079558846 date "2013-05-02" @default.
• W2079558846 modified "2023-10-03" @default.
• W2079558846 title "Effects of the Chromatic Defocus Caused by Interchange of Two Monochromatic Lights on Refraction and Ocular Dimension in Guinea Pigs" @default.
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• W2079558846 doi "https://doi.org/10.1371/journal.pone.0063229" @default.
• W2079558846 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3642148" @default.
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