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- W2079559622 abstract "SCHWARTZ et al. observed that certain commercially obtainable hæmatoporphyrin preparations were contaminated by a porphyrin capable of becoming localized in experimental tumours1,2, and that pure hæmatoporphyrin was unable to do so. These findings gave the impetus to the present work on halogenoporphyrins. The premise on the basis of which halogenoporphyrins were chosen was the assumption that the aforementioned impurity represents an intermediate formed in the course of the synthesis of hæmatoporphyrin from hæmin. One such intermediate could be bis-(2-bromo-ethyl)deuteroporphyrin. Since iodine–131 is a more convenient isotope for the purpose of labelling than isotopes of bromine, the iodine 131–labelled analogue was synthesized." @default.
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- W2079559622 date "1960-09-01" @default.
- W2079559622 modified "2023-09-27" @default.
- W2079559622 title "Localization of a Halogenated Porphyrin in Mouse Tumours" @default.
- W2079559622 doi "https://doi.org/10.1038/1871124a0" @default.
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