FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079565425> ?p ?o ?g. }

• W2079565425 endingPage "76" @default.
• W2079565425 startingPage "68" @default.
• W2079565425 abstract "In this paper, a quantitative structure-retention relationship (QSRR) method is employed to model the retention behaviour in reversed-phase high-performance liquid chromatography of arylpropionic acid derivatives, largely used non-steroidal anti-inflammatory drugs (NSAIDs). Computed molecular descriptors and the organic modifier content in the mobile phase are associated into a comprehensive model to describe the effect of both solute structure and eluent composition on the isocratic retention of these drugs in water-acetonitrile mobile phases. Multilinear regression (MLR) combined with genetic algorithm (GA) variable selection is used to extract from a large set of computed 3D descriptors an optimal subset. Based on GA-MLR analysis, a five-dimensional QSRR model is identified. All the four selected molecular descriptors belong to the category of GEometry, Topology, and Atom-Weights AssemblY (GETAWAY) descriptors. The related multilinear model exhibits a quite good fitting and predictive performance. This model is further improved using an artificial neural network (ANN) learned by error back-propagation. Finally, the ANN-based model displays a remarkably better performance as compared with the MLR counterpart and, based on external validation, is able to predict with good accuracy the behaviour of unknown arylpropionic NSAIDs in the range of mobile phase composition of analytical interest (between 35 and 75% acetonitrile (v/v))." @default.
• W2079565425 created "2016-06-24" @default.
• W2079565425 creator A5026832832 @default.
• W2079565425 creator A5041802206 @default.
• W2079565425 creator A5041837071 @default.
• W2079565425 creator A5048393080 @default.
• W2079565425 creator A5050824917 @default.
• W2079565425 date "2007-10-01" @default.
• W2079565425 modified "2023-10-11" @default.
• W2079565425 title "Investigation of retention behaviour of non-steroidal anti-inflammatory drugs in high-performance liquid chromatography by using quantitative structure–retention relationships" @default.
• W2079565425 cites W1567533735 @default.
• W2079565425 cites W1608086260 @default.
• W2079565425 cites W184671227 @default.
• W2079565425 cites W1968614037 @default.
• W2079565425 cites W1968665806 @default.
• W2079565425 cites W1980002593 @default.
• W2079565425 cites W1985966715 @default.
• W2079565425 cites W1986453686 @default.
• W2079565425 cites W1989840966 @default.
• W2079565425 cites W1993180192 @default.
• W2079565425 cites W2004076168 @default.
• W2079565425 cites W2004372324 @default.
• W2079565425 cites W2005020926 @default.
• W2079565425 cites W2007725875 @default.
• W2079565425 cites W2011588810 @default.
• W2079565425 cites W2015782540 @default.
• W2079565425 cites W2015870870 @default.
• W2079565425 cites W2020603228 @default.
• W2079565425 cites W2022015963 @default.
• W2079565425 cites W2024571408 @default.
• W2079565425 cites W2028193319 @default.
• W2079565425 cites W2037730130 @default.
• W2079565425 cites W2038242977 @default.
• W2079565425 cites W2058250168 @default.
• W2079565425 cites W2063071144 @default.
• W2079565425 cites W2065141204 @default.
• W2079565425 cites W2069610606 @default.
• W2079565425 cites W2070972624 @default.
• W2079565425 cites W2075440412 @default.
• W2079565425 cites W2075613930 @default.
• W2079565425 cites W2090162906 @default.
• W2079565425 cites W2095418180 @default.
• W2079565425 cites W2128325314 @default.
• W2079565425 cites W2131124255 @default.
• W2079565425 cites W2152629484 @default.
• W2079565425 cites W4211019543 @default.
• W2079565425 doi "https://doi.org/10.1016/j.aca.2007.08.026" @default.
• W2079565425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17904471" @default.
• W2079565425 hasPublicationYear "2007" @default.
• W2079565425 type Work @default.
• W2079565425 sameAs 2079565425 @default.
• W2079565425 citedByCount "41" @default.
• W2079565425 countsByYear W20795654252012 @default.
• W2079565425 countsByYear W20795654252013 @default.
• W2079565425 countsByYear W20795654252014 @default.
• W2079565425 countsByYear W20795654252015 @default.
• W2079565425 countsByYear W20795654252016 @default.
• W2079565425 countsByYear W20795654252017 @default.
• W2079565425 countsByYear W20795654252018 @default.
• W2079565425 countsByYear W20795654252019 @default.
• W2079565425 countsByYear W20795654252021 @default.
• W2079565425 countsByYear W20795654252022 @default.
• W2079565425 crossrefType "journal-article" @default.
• W2079565425 hasAuthorship W2079565425A5026832832 @default.
• W2079565425 hasAuthorship W2079565425A5041802206 @default.
• W2079565425 hasAuthorship W2079565425A5041837071 @default.
• W2079565425 hasAuthorship W2079565425A5048393080 @default.
• W2079565425 hasAuthorship W2079565425A5050824917 @default.
• W2079565425 hasConcept C113196181 @default.
• W2079565425 hasConcept C154945302 @default.
• W2079565425 hasConcept C164126121 @default.
• W2079565425 hasConcept C164923092 @default.
• W2079565425 hasConcept C178790620 @default.
• W2079565425 hasConcept C179998833 @default.
• W2079565425 hasConcept C185592680 @default.
• W2079565425 hasConcept C186060115 @default.
• W2079565425 hasConcept C202444582 @default.
• W2079565425 hasConcept C2777463227 @default.
• W2079565425 hasConcept C3020018676 @default.
• W2079565425 hasConcept C33923547 @default.
• W2079565425 hasConcept C41008148 @default.
• W2079565425 hasConcept C43617362 @default.
• W2079565425 hasConcept C44280652 @default.
• W2079565425 hasConcept C45188465 @default.
• W2079565425 hasConcept C50644808 @default.
• W2079565425 hasConcept C71240020 @default.
• W2079565425 hasConcept C84392682 @default.
• W2079565425 hasConcept C86803240 @default.
• W2079565425 hasConceptScore W2079565425C113196181 @default.
• W2079565425 hasConceptScore W2079565425C154945302 @default.
• W2079565425 hasConceptScore W2079565425C164126121 @default.
• W2079565425 hasConceptScore W2079565425C164923092 @default.
• W2079565425 hasConceptScore W2079565425C178790620 @default.
• W2079565425 hasConceptScore W2079565425C179998833 @default.
• W2079565425 hasConceptScore W2079565425C185592680 @default.
• W2079565425 hasConceptScore W2079565425C186060115 @default.
• W2079565425 hasConceptScore W2079565425C202444582 @default.
• W2079565425 hasConceptScore W2079565425C2777463227 @default.

• next