FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079568089> ?p ?o ?g. }

• W2079568089 endingPage "3680" @default.
• W2079568089 startingPage "3673" @default.
• W2079568089 abstract "Examination of supernatant fractions from broth cultures of Lactobacillus fermentum BR11 revealed the presence of a number of proteins, including a 27-kDa protein termed Sep. The amino-terminal sequence of Sep was determined, and the gene encoding it was cloned and sequenced. Sep is a 205-amino-acid protein and contains a 30-amino-acid secretion signal and has overall homology (between 39 and 92% identity) with similarly sized proteins of Lactobacillus reuteri, Enterococcus faecium, Streptococcus pneumoniae, Streptococcus agalactiae, and Lactobacillus plantarum. The carboxy-terminal 81 amino acids of Sep also have strong homology (86% identity) to the carboxy termini of the aggregation-promoting factor (APF) surface proteins of Lactobacillus gasseri and Lactobacillus johnsonii. The mature amino terminus of Sep contains a putative peptidoglycan-binding LysM domain, thereby making it distinct from APF proteins. We have identified a common motif within LysM domains that is shared with carbohydrate binding YG motifs which are found in streptococcal glucan-binding proteins and glucosyltransferases. Sep was investigated as a heterologous peptide expression vector in L. fermentum, Lactobacillus rhamnosus GG and Lactococcus lactis MG1363. Modified Sep containing an amino-terminal six-histidine epitope was found associated with the cells but was largely present in the supernatant in the L. fermentum, L. rhamnosus, and L. lactis hosts. Sep as well as the previously described surface protein BspA were used to express and secrete in L. fermentum or L. rhamnosus a fragment of human E-cadherin, which contains the receptor region for Listeria monocytogenes. This study demonstrates that Sep has potential for heterologous protein expression and export in lactic acid bacteria." @default.
• W2079568089 created "2016-06-24" @default.
• W2079568089 creator A5023336277 @default.
• W2079568089 creator A5028863296 @default.
• W2079568089 creator A5049561419 @default.
• W2079568089 creator A5055370710 @default.
• W2079568089 date "2004-06-01" @default.
• W2079568089 modified "2023-10-16" @default.
• W2079568089 title "Identification and Characterization of the Novel LysM Domain-Containing Surface Protein Sep from <i>Lactobacillus fermentum</i> BR11 and Its Use as a Peptide Fusion Partner in <i>Lactobacillus</i> and <i>Lactococcus</i>" @default.
• W2079568089 cites W1481121752 @default.
• W2079568089 cites W1537205292 @default.
• W2079568089 cites W1551260639 @default.
• W2079568089 cites W1767841940 @default.
• W2079568089 cites W1999870427 @default.
• W2079568089 cites W2001553481 @default.
• W2079568089 cites W2013682169 @default.
• W2079568089 cites W2032932328 @default.
• W2079568089 cites W2042133316 @default.
• W2079568089 cites W2043904270 @default.
• W2079568089 cites W2078050471 @default.
• W2079568089 cites W2098879229 @default.
• W2079568089 cites W2100824730 @default.
• W2079568089 cites W2103667123 @default.
• W2079568089 cites W2109105334 @default.
• W2079568089 cites W2109276669 @default.
• W2079568089 cites W2109418916 @default.
• W2079568089 cites W2110042660 @default.
• W2079568089 cites W2111485203 @default.
• W2079568089 cites W2111564369 @default.
• W2079568089 cites W2111752110 @default.
• W2079568089 cites W2128030385 @default.
• W2079568089 cites W2130485553 @default.
• W2079568089 cites W2140544780 @default.
• W2079568089 cites W2142456288 @default.
• W2079568089 cites W2143649821 @default.
• W2079568089 cites W2144739912 @default.
• W2079568089 cites W2145683869 @default.
• W2079568089 cites W2146052711 @default.
• W2079568089 cites W2153038986 @default.
• W2079568089 cites W2156319674 @default.
• W2079568089 cites W2163480997 @default.
• W2079568089 cites W2169510298 @default.
• W2079568089 cites W2170211948 @default.
• W2079568089 doi "https://doi.org/10.1128/aem.70.6.3673-3680.2004" @default.
• W2079568089 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/427774" @default.
• W2079568089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15184172" @default.
• W2079568089 hasPublicationYear "2004" @default.
• W2079568089 type Work @default.
• W2079568089 sameAs 2079568089 @default.
• W2079568089 citedByCount "42" @default.
• W2079568089 countsByYear W20795680892013 @default.
• W2079568089 countsByYear W20795680892014 @default.
• W2079568089 countsByYear W20795680892015 @default.
• W2079568089 countsByYear W20795680892016 @default.
• W2079568089 countsByYear W20795680892017 @default.
• W2079568089 countsByYear W20795680892018 @default.
• W2079568089 countsByYear W20795680892019 @default.
• W2079568089 countsByYear W20795680892020 @default.
• W2079568089 countsByYear W20795680892021 @default.
• W2079568089 countsByYear W20795680892023 @default.
• W2079568089 crossrefType "journal-article" @default.
• W2079568089 hasAuthorship W2079568089A5023336277 @default.
• W2079568089 hasAuthorship W2079568089A5028863296 @default.
• W2079568089 hasAuthorship W2079568089A5049561419 @default.
• W2079568089 hasAuthorship W2079568089A5055370710 @default.
• W2079568089 hasBestOaLocation W20795680891 @default.
• W2079568089 hasConcept C100544194 @default.
• W2079568089 hasConcept C104317684 @default.
• W2079568089 hasConcept C167625842 @default.
• W2079568089 hasConcept C2775898472 @default.
• W2079568089 hasConcept C2775920511 @default.
• W2079568089 hasConcept C2776503186 @default.
• W2079568089 hasConcept C2776651480 @default.
• W2079568089 hasConcept C2778536940 @default.
• W2079568089 hasConcept C2778985185 @default.
• W2079568089 hasConcept C2780011460 @default.
• W2079568089 hasConcept C2780206646 @default.
• W2079568089 hasConcept C515207424 @default.
• W2079568089 hasConcept C523546767 @default.
• W2079568089 hasConcept C54355233 @default.
• W2079568089 hasConcept C55493867 @default.
• W2079568089 hasConcept C86803240 @default.
• W2079568089 hasConcept C89423630 @default.
• W2079568089 hasConceptScore W2079568089C100544194 @default.
• W2079568089 hasConceptScore W2079568089C104317684 @default.
• W2079568089 hasConceptScore W2079568089C167625842 @default.
• W2079568089 hasConceptScore W2079568089C2775898472 @default.
• W2079568089 hasConceptScore W2079568089C2775920511 @default.
• W2079568089 hasConceptScore W2079568089C2776503186 @default.
• W2079568089 hasConceptScore W2079568089C2776651480 @default.
• W2079568089 hasConceptScore W2079568089C2778536940 @default.
• W2079568089 hasConceptScore W2079568089C2778985185 @default.
• W2079568089 hasConceptScore W2079568089C2780011460 @default.
• W2079568089 hasConceptScore W2079568089C2780206646 @default.
• W2079568089 hasConceptScore W2079568089C515207424 @default.
• W2079568089 hasConceptScore W2079568089C523546767 @default.
• W2079568089 hasConceptScore W2079568089C54355233 @default.
• W2079568089 hasConceptScore W2079568089C55493867 @default.

• next