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- W2079576736 abstract "Studies were undertaken to determinethe effects of intravenous infusions of bovinetesticular extracts on plasma levels of FSH and LHin castrate male sheep. Decapsulated bovine testeswere homogenized with phosphate buffer, thehomogenates centrifuged at 30,000 ×g for 30 min, and the supernatants extracted with diethyl ether. The aqueous extracts were filtered using DiafloXM-100 membranes and the ultra-filtrates lyophilized. The extracts were infused over 24 hours, and plasma FSH and LH were measured prior to, during, and after the infusion. Control studies usinginfusions of saline and liver extracts demonstratedno decrease in FSH levels in 6 out of 7 controls, while LH levels tended to rise. Following infusionswith the testicular extracts, the levels of FSH wereselectively decreased to between 42% and 85% ofbaseline levels, and they subsequently remainedsuppressed for at least 24 hours. These resultssuggest that the testis is the site of production of awater-soluble, non-steroidal substance whichexerts an i..." @default.
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- W2079576736 date "1976-08-01" @default.
- W2079576736 modified "2023-09-27" @default.
- W2079576736 title "SELECTIVE SUPPRESSION OF FSH BY TESTICULAR EXTRACTS" @default.
- W2079576736 doi "https://doi.org/10.1097/00006254-197608000-00014" @default.
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