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- W2079579456 abstract "Rapid-eye-movement (REM) sleep behavior disorder (RBD) is an injurious parasomnia that mainly affects older men who act out violent dreams (Thorpy 1990). Although there is an animal model of RBD induced by bilateral pontine tegmental lesions, human RBD is associated with diverse neurologic disorders, which usually spare the brain stem, in approximately half of reported cases (Schenck et al 1993). In the other half of reported cases, RBD has been considered to be an idiopathic condition, although this view must now be revised in light of new data indicating that 38% of a group of 29 older men initially diagnosed with idiopathic RBD eventually developed a parkinsonian disorder (Schenck et al 1996). Published autopsy data in RBD are scarce. Since RBD was formally identified in 1985, to our knowledge there has been one report presenting postmortem brain findings in RBD. In that report, incidental Lewy body disease, with marked decrease of pigmented neurons in the locus coeruleus and substantia nigra, was identified in a 84-year-old man who had a 20-year history of" @default.
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- W2079579456 date "1996-09-01" @default.
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- W2079579456 title "A case of REM sleep behavior disorder with autopsy-confirmed alzheimer's disease: postmortem brain stem histochemical analyses" @default.
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- W2079579456 doi "https://doi.org/10.1016/0006-3223(96)00070-4" @default.
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