FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079583497> ?p ?o ?g. }

• W2079583497 endingPage "571" @default.
• W2079583497 startingPage "564" @default.
• W2079583497 abstract "The study evaluated the adulterants in a specimen of illicit street heroin supplied under strict control by the Pakistan Anti-Narcotic Force. It also examined the effects of Hypericum perforatum L. extracts on the naloxone-induced heroin withdrawal syndrome. The GC-MS analysis of the specimen showed that in addition to heroin (37.8%), the sample also contained caffeine (8.4%), phenobarbitone (12.7%), 6-acetyl codeine (5.3%), 6-acetyl morphine (10.9%) and noscapine (15.8%). Administration of the heroin to rats for 8 days induced physical withdrawal signs of abdominal constriction, diarrhoea and vocalization on touch after naloxone treatment. Aqueous Hypericum perforatum extracts (20 mg/kg twice daily chronically or as a single acute dose 90 min before naloxone) given orally to the heroin dependent rats attenuated abdominal constrictions both acutely and chronically while the hydroethanol and ethanol extracts were only effective in acutely treated animals. Diarrhoea was ameliorated by the hydroethanol and ethanol extracts following acute or chronic heroin treatment while the aqueous extract failed to show any effect. Vocalization on touch during withdrawal was reduced by all the extracts either chronically or acutely with the exception of chronic treatment with hydroethanol extracts. The findings suggest that Hypericum perforatum is capable of reducing the physical signs of opiate withdrawal." @default.
• W2079583497 created "2016-06-24" @default.
• W2079583497 creator A5022734958 @default.
• W2079583497 creator A5028465023 @default.
• W2079583497 creator A5090283879 @default.
• W2079583497 date "2009-04-01" @default.
• W2079583497 modified "2023-10-13" @default.
• W2079583497 title "Adulterant profile of illicit street heroin and reduction of its precipitated physical dependence withdrawal syndrome by extracts of St John's wort (<i>Hypericum perforatum</i>)" @default.
• W2079583497 cites W1981919773 @default.
• W2079583497 cites W1982774938 @default.
• W2079583497 cites W1984095516 @default.
• W2079583497 cites W1985062152 @default.
• W2079583497 cites W1994422722 @default.
• W2079583497 cites W1998959849 @default.
• W2079583497 cites W2000904856 @default.
• W2079583497 cites W2025380973 @default.
• W2079583497 cites W2027892376 @default.
• W2079583497 cites W2031556005 @default.
• W2079583497 cites W2036309374 @default.
• W2079583497 cites W2040670788 @default.
• W2079583497 cites W2046940985 @default.
• W2079583497 cites W2049302358 @default.
• W2079583497 cites W2060006930 @default.
• W2079583497 cites W2061054592 @default.
• W2079583497 cites W2063297111 @default.
• W2079583497 cites W2066898478 @default.
• W2079583497 cites W2069707229 @default.
• W2079583497 cites W2073220272 @default.
• W2079583497 cites W2085156822 @default.
• W2079583497 cites W2087221285 @default.
• W2079583497 cites W2093705793 @default.
• W2079583497 cites W2098185806 @default.
• W2079583497 cites W2118248851 @default.
• W2079583497 cites W2119974823 @default.
• W2079583497 cites W3162421942 @default.
• W2079583497 cites W4252880542 @default.
• W2079583497 doi "https://doi.org/10.1002/ptr.2692" @default.
• W2079583497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19067385" @default.
• W2079583497 hasPublicationYear "2009" @default.
• W2079583497 type Work @default.
• W2079583497 sameAs 2079583497 @default.
• W2079583497 citedByCount "14" @default.
• W2079583497 countsByYear W20795834972012 @default.
• W2079583497 countsByYear W20795834972013 @default.
• W2079583497 countsByYear W20795834972014 @default.
• W2079583497 countsByYear W20795834972015 @default.
• W2079583497 countsByYear W20795834972016 @default.
• W2079583497 countsByYear W20795834972021 @default.
• W2079583497 countsByYear W20795834972022 @default.
• W2079583497 crossrefType "journal-article" @default.
• W2079583497 hasAuthorship W2079583497A5022734958 @default.
• W2079583497 hasAuthorship W2079583497A5028465023 @default.
• W2079583497 hasAuthorship W2079583497A5090283879 @default.
• W2079583497 hasConcept C126322002 @default.
• W2079583497 hasConcept C170493617 @default.
• W2079583497 hasConcept C2775849661 @default.
• W2079583497 hasConcept C2776651039 @default.
• W2079583497 hasConcept C2777389121 @default.
• W2079583497 hasConcept C2777866328 @default.
• W2079583497 hasConcept C2778195246 @default.
• W2079583497 hasConcept C2778750930 @default.
• W2079583497 hasConcept C2778903686 @default.
• W2079583497 hasConcept C2780035454 @default.
• W2079583497 hasConcept C2781063702 @default.
• W2079583497 hasConcept C42219234 @default.
• W2079583497 hasConcept C556039675 @default.
• W2079583497 hasConcept C71924100 @default.
• W2079583497 hasConcept C98274493 @default.
• W2079583497 hasConceptScore W2079583497C126322002 @default.
• W2079583497 hasConceptScore W2079583497C170493617 @default.
• W2079583497 hasConceptScore W2079583497C2775849661 @default.
• W2079583497 hasConceptScore W2079583497C2776651039 @default.
• W2079583497 hasConceptScore W2079583497C2777389121 @default.
• W2079583497 hasConceptScore W2079583497C2777866328 @default.
• W2079583497 hasConceptScore W2079583497C2778195246 @default.
• W2079583497 hasConceptScore W2079583497C2778750930 @default.
• W2079583497 hasConceptScore W2079583497C2778903686 @default.
• W2079583497 hasConceptScore W2079583497C2780035454 @default.
• W2079583497 hasConceptScore W2079583497C2781063702 @default.
• W2079583497 hasConceptScore W2079583497C42219234 @default.
• W2079583497 hasConceptScore W2079583497C556039675 @default.
• W2079583497 hasConceptScore W2079583497C71924100 @default.
• W2079583497 hasConceptScore W2079583497C98274493 @default.
• W2079583497 hasIssue "4" @default.
• W2079583497 hasLocation W20795834971 @default.
• W2079583497 hasLocation W20795834972 @default.
• W2079583497 hasOpenAccess W2079583497 @default.
• W2079583497 hasPrimaryLocation W20795834971 @default.
• W2079583497 hasRelatedWork W1997230612 @default.
• W2079583497 hasRelatedWork W2019410252 @default.
• W2079583497 hasRelatedWork W2061600341 @default.
• W2079583497 hasRelatedWork W2169052762 @default.
• W2079583497 hasRelatedWork W2253194622 @default.
• W2079583497 hasRelatedWork W2390193836 @default.
• W2079583497 hasRelatedWork W2393160891 @default.
• W2079583497 hasRelatedWork W2400257126 @default.
• W2079583497 hasRelatedWork W2640369019 @default.
• W2079583497 hasRelatedWork W4232292971 @default.

• next