FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079586036> ?p ?o ?g. }

• W2079586036 endingPage "196" @default.
• W2079586036 startingPage "189" @default.
• W2079586036 abstract "Schistosoma mansoni-infected mice tend to present with either one of two different hepatic pathological patterns during chronic infection: periportal fibrosis (PF) with portal concentration of periovular granulomas and fibrosis or isolated granulomas (IG), with scattered periovular granulomas within the liver. These are models for the two clinical presentations of schistosomiasis, the severe hepatosplenic and the mild intestinal forms. In the present work, we examined the relationship between the development of these histopathological aspects and immunological markers in S. mansoni-infected mice. Although BALB/c mice with PF and IG had similar egg numbers in the liver, PF mice had higher liver collagen contents than mice with IG. Cultured spleen cells from mice with PF and IG had similar proliferation 20 and 40 weeks after S. mansoni infection upon stimulation with parasite egg antigen (SEA) or mitogen (Con A). Production of IL-4 upon SEA stimulation was higher in cell cultures from mice with PF, whereas IL-5 and IFN-gamma levels were not statistically different between PF and IG groups. Mice with IG had similar serum concentrations of total IgE and anti-SEA IgG1, IgG2a, IgG2b and IgG3 compared to sera from PF mice. Levels of IgG1 and IgG2a antibodies were the highest and the lowest detected, respectively. In conclusion, isogenic BALB/c mice infected with S. mansoni that develop periportal fibrosis or isolated granulomas have similar immunological patterns despite the two pathologic forms of schistosomal liver fibrosis." @default.
• W2079586036 created "2016-06-24" @default.
• W2079586036 creator A5018728445 @default.
• W2079586036 creator A5040824560 @default.
• W2079586036 creator A5051741247 @default.
• W2079586036 creator A5064970697 @default.
• W2079586036 creator A5082048113 @default.
• W2079586036 date "2004-07-01" @default.
• W2079586036 modified "2023-10-18" @default.
• W2079586036 title "Comparison of immune responses of Schistosoma mansoni-infected mice with distinct chronic forms of the disease" @default.
• W2079586036 cites W162978041 @default.
• W2079586036 cites W1826427675 @default.
• W2079586036 cites W1965366343 @default.
• W2079586036 cites W1969583375 @default.
• W2079586036 cites W1977250707 @default.
• W2079586036 cites W1984208029 @default.
• W2079586036 cites W1998663447 @default.
• W2079586036 cites W2001872263 @default.
• W2079586036 cites W2006561061 @default.
• W2079586036 cites W2008447940 @default.
• W2079586036 cites W2011675865 @default.
• W2079586036 cites W2024376831 @default.
• W2079586036 cites W2034360312 @default.
• W2079586036 cites W2055502077 @default.
• W2079586036 cites W2066348883 @default.
• W2079586036 cites W2084168776 @default.
• W2079586036 cites W2093913255 @default.
• W2079586036 cites W2094737914 @default.
• W2079586036 cites W2148950326 @default.
• W2079586036 cites W2156272421 @default.
• W2079586036 cites W2170713735 @default.
• W2079586036 doi "https://doi.org/10.1016/j.actatropica.2004.05.008" @default.
• W2079586036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15234668" @default.
• W2079586036 hasPublicationYear "2004" @default.
• W2079586036 type Work @default.
• W2079586036 sameAs 2079586036 @default.
• W2079586036 citedByCount "17" @default.
• W2079586036 countsByYear W20795860362013 @default.
• W2079586036 countsByYear W20795860362014 @default.
• W2079586036 countsByYear W20795860362015 @default.
• W2079586036 countsByYear W20795860362021 @default.
• W2079586036 countsByYear W20795860362022 @default.
• W2079586036 crossrefType "journal-article" @default.
• W2079586036 hasAuthorship W2079586036A5018728445 @default.
• W2079586036 hasAuthorship W2079586036A5040824560 @default.
• W2079586036 hasAuthorship W2079586036A5051741247 @default.
• W2079586036 hasAuthorship W2079586036A5064970697 @default.
• W2079586036 hasAuthorship W2079586036A5082048113 @default.
• W2079586036 hasBestOaLocation W20795860362 @default.
• W2079586036 hasConcept C141105273 @default.
• W2079586036 hasConcept C142724271 @default.
• W2079586036 hasConcept C147483822 @default.
• W2079586036 hasConcept C159654299 @default.
• W2079586036 hasConcept C165901193 @default.
• W2079586036 hasConcept C203014093 @default.
• W2079586036 hasConcept C2776225656 @default.
• W2079586036 hasConcept C2776863245 @default.
• W2079586036 hasConcept C2778491710 @default.
• W2079586036 hasConcept C2779726973 @default.
• W2079586036 hasConcept C2780140890 @default.
• W2079586036 hasConcept C2780559512 @default.
• W2079586036 hasConcept C2780931953 @default.
• W2079586036 hasConcept C71924100 @default.
• W2079586036 hasConcept C86803240 @default.
• W2079586036 hasConcept C8891405 @default.
• W2079586036 hasConceptScore W2079586036C141105273 @default.
• W2079586036 hasConceptScore W2079586036C142724271 @default.
• W2079586036 hasConceptScore W2079586036C147483822 @default.
• W2079586036 hasConceptScore W2079586036C159654299 @default.
• W2079586036 hasConceptScore W2079586036C165901193 @default.
• W2079586036 hasConceptScore W2079586036C203014093 @default.
• W2079586036 hasConceptScore W2079586036C2776225656 @default.
• W2079586036 hasConceptScore W2079586036C2776863245 @default.
• W2079586036 hasConceptScore W2079586036C2778491710 @default.
• W2079586036 hasConceptScore W2079586036C2779726973 @default.
• W2079586036 hasConceptScore W2079586036C2780140890 @default.
• W2079586036 hasConceptScore W2079586036C2780559512 @default.
• W2079586036 hasConceptScore W2079586036C2780931953 @default.
• W2079586036 hasConceptScore W2079586036C71924100 @default.
• W2079586036 hasConceptScore W2079586036C86803240 @default.
• W2079586036 hasConceptScore W2079586036C8891405 @default.
• W2079586036 hasIssue "2" @default.
• W2079586036 hasLocation W20795860361 @default.
• W2079586036 hasLocation W20795860362 @default.
• W2079586036 hasLocation W20795860363 @default.
• W2079586036 hasOpenAccess W2079586036 @default.
• W2079586036 hasPrimaryLocation W20795860361 @default.
• W2079586036 hasRelatedWork W1759882342 @default.
• W2079586036 hasRelatedWork W1985209512 @default.
• W2079586036 hasRelatedWork W2001055320 @default.
• W2079586036 hasRelatedWork W2025043733 @default.
• W2079586036 hasRelatedWork W202973276 @default.
• W2079586036 hasRelatedWork W2065548809 @default.
• W2079586036 hasRelatedWork W2097979284 @default.
• W2079586036 hasRelatedWork W2220102944 @default.
• W2079586036 hasRelatedWork W2413773413 @default.
• W2079586036 hasRelatedWork W2416822640 @default.
• W2079586036 hasVolume "91" @default.

• next