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• W2079600581 abstract "A series of alpha-methylene penicillins was synthesized and SAR were studied. The alpha-isomers were found to be chemically reactive and biologically active in contrast to the beta-isomers. In addition, the alpha-isomers have broader spectrum of in vitro activity than the corresponding penicillins. Generally, the alpha-isomers are more active against gram-negative bacteria than the corresponding penicillins, but slightly weaker in potency towards gram-positive organisms." @default.
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• W2079600581 date "1993-09-01" @default.
• W2079600581 modified "2023-09-27" @default.
• W2079600581 title "(2,3)-(α-methylenepenams: Synthesis and in vitro activity" @default.
• W2079600581 cites W1592146281 @default.
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• W2079600581 doi "https://doi.org/10.1016/s0968-0896(00)82118-5" @default.
• W2079600581 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8081849" @default.
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