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• W2079632351 abstract "The translational mobility of fluorescent-labeled monoclonal antibodies specifically bound to supported phospholipid bilayers containing hapten-conjugated phospholipids has been measured as a function of the surface concentration of bound antibodies using fluorescence recovery after photobleaching. Fluorescence recovery curves are fit well by a model that assumes the presence of two populations of antibodies with different lateral diffusion coefficients. The larger diffusion coefficient equals 3.5 x 10(-9) cm2/s, the smaller diffusion coefficient ranges from 1.5 x 10(-9) cm2/s to 2.5 x 10(-10) cm2/s, and the fractional fluorescence recovery associated with the smaller coefficient increases from approximately 0 to approximately 0.7 with increasing concentration of bound antibody. These results suggest that complexes of haptenated phospholipids and antibodies in phospholipid Langmuir-Blodgett films form clusters or domains in a concentration-dependent fashion." @default.
• W2079632351 created "2016-06-24" @default.
• W2079632351 creator A5045301534 @default.
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• W2079632351 date "1988-09-01" @default.
• W2079632351 modified "2023-09-27" @default.
• W2079632351 title "Inhomogeneous translational diffusion of monoclonal antibodies on phospholipid Langmuir-Blodgett films" @default.
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• W2079632351 doi "https://doi.org/10.1016/s0006-3495(88)82979-5" @default.
• W2079632351 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1330345" @default.
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