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- W2079652085 abstract "Processing of RNA precursors to their mature form often occurs co-transcriptionally. Consequently, the ternary complex of DNA template, RNA polymerase and nascent RNA chain is the physiological substrate for factors that modify the nascent RNA by capping, splicing and cleavage/polyadenylation. mRNA production is thought to occur within a factory that contains the RNA polymerase II transcription machine and the processing machines. Newly discovered protein-protein contacts between RNA polymerase and factors that process mRNA precursors are beginning to illuminate how the mRNA factory works." @default.
- W2079652085 created "2016-06-24" @default.
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- W2079652085 date "2002-06-01" @default.
- W2079652085 modified "2023-10-16" @default.
- W2079652085 title "The mRNA assembly line: transcription and processing machines in the same factory" @default.
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- W2079652085 doi "https://doi.org/10.1016/s0955-0674(02)00333-2" @default.
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