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• W2079652743 abstract "Background Clostridium difficile (CD), a gram-positive rod bacterium, resides normally within the human colon. Antibiotic treatment alters normal colonic flora, potentiating abnormal overgrowth of CD. Methods This study examined the 2004 to 2006 Nationwide Inpatient Sample to determine outcomes of CD colitis after 695,010 elective colonic resections. Results CD infection, occurring in 1.4% of patients, was associated with higher pulmonary (12.1% vs 6.4%) and gastrointestinal (12.8% vs 10.5%) complications as well as an increased length of stay (22.6 vs 10.9 days) and mortality (16.2% vs 4.9%; all P < .001). CD colitis patients more frequently held Medicare insurance (68% vs 51%) and underwent small segmental colonic resection as opposed to a defined anatomic resection (20.0% vs 9.9%; P < .001). An underlying diagnosis of colon cancer was associated with a lower incidence of CD colitis (odds ratio, .71; 95% confidence interval, .59–.84; P < .001). Conclusions CD colitis is associated with worse outcomes after elective colonic resection." @default.
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• W2079652743 date "2011-02-01" @default.
• W2079652743 modified "2023-10-18" @default.
• W2079652743 title "The morbidity of Clostridium difficile infection after elective colonic resection—results from a national population database" @default.
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• W2079652743 doi "https://doi.org/10.1016/j.amjsurg.2010.09.017" @default.
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• W2079652743 hasPublicationYear "2011" @default.
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