Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079653675> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2079653675 endingPage "171" @default.
- W2079653675 startingPage "162" @default.
- W2079653675 abstract "Whole-body autoradiography with 3H-labelled aflatoxin B1 (3H-AFB1) in C57B1-mice showed a pronounced accumulation and retention of radioactivity in some nasal glands. At long survival intervals the labelling of the nasal glands was much higher than that of the liver. Experiments in vitro showed a capacity of the nasal glands to form tissue-bound 3H-AFB1-metabolites. Incubations in the presence of glutathione decreased the levels of tissue-bound 3H-AFB1-metabolites both in the liver and in the nasal glands, but the decrease was more pronounced in the former than in the latter tissue. The 3H-AFB1-metabolite-binding to the nasal glands in vitro was inhibited by the cytochrome P-450-inhibitor metyrapone and by CO- and N2-atmospheres indicating a cytochrome P-450-dependent bioactivation of the AFB1 in these glands. Cytochrome P-450 was shown to be present in the glands although at a much lower level than in the liver. The glands in the nose, which were shown to have this AFB1-metabolizing capacity, were the lateral nasal gland (Steno's gland) situated ventrally and laterally to the maxillary sinus and the large group of glands in the lateral nasal wall ventrally to the ostium of the maxillary sinus. Our results also indicated an AFB1 -metabolizing capacity of the serous glands which are present in the anterior part of the nasal septum." @default.
- W2079653675 created "2016-06-24" @default.
- W2079653675 creator A5035799046 @default.
- W2079653675 creator A5048023260 @default.
- W2079653675 creator A5071237663 @default.
- W2079653675 date "1990-08-01" @default.
- W2079653675 modified "2023-10-12" @default.
- W2079653675 title "Disposition of3H-Aflatoxin B1in Mice: Formation and Retention of Tissue Bound Metabolites in Nasal Glands" @default.
- W2079653675 cites W1775749144 @default.
- W2079653675 cites W1949640598 @default.
- W2079653675 cites W1951469402 @default.
- W2079653675 cites W2018204743 @default.
- W2079653675 cites W2030575145 @default.
- W2079653675 cites W2049510239 @default.
- W2079653675 cites W2054979333 @default.
- W2079653675 cites W2055851127 @default.
- W2079653675 cites W2058474351 @default.
- W2079653675 cites W2059456354 @default.
- W2079653675 cites W2070384173 @default.
- W2079653675 cites W2073788781 @default.
- W2079653675 cites W2074815894 @default.
- W2079653675 cites W2080305427 @default.
- W2079653675 cites W2111574675 @default.
- W2079653675 cites W2140665964 @default.
- W2079653675 doi "https://doi.org/10.1111/j.1600-0773.1990.tb00805.x" @default.
- W2079653675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2123983" @default.
- W2079653675 hasPublicationYear "1990" @default.
- W2079653675 type Work @default.
- W2079653675 sameAs 2079653675 @default.
- W2079653675 citedByCount "11" @default.
- W2079653675 countsByYear W20796536752014 @default.
- W2079653675 countsByYear W20796536752018 @default.
- W2079653675 crossrefType "journal-article" @default.
- W2079653675 hasAuthorship W2079653675A5035799046 @default.
- W2079653675 hasAuthorship W2079653675A5048023260 @default.
- W2079653675 hasAuthorship W2079653675A5071237663 @default.
- W2079653675 hasConcept C105702510 @default.
- W2079653675 hasConcept C126322002 @default.
- W2079653675 hasConcept C134018914 @default.
- W2079653675 hasConcept C15310415 @default.
- W2079653675 hasConcept C185592680 @default.
- W2079653675 hasConcept C2776719974 @default.
- W2079653675 hasConcept C2777477808 @default.
- W2079653675 hasConcept C2778311950 @default.
- W2079653675 hasConcept C526171541 @default.
- W2079653675 hasConcept C59377437 @default.
- W2079653675 hasConcept C62231903 @default.
- W2079653675 hasConcept C71924100 @default.
- W2079653675 hasConcept C86803240 @default.
- W2079653675 hasConceptScore W2079653675C105702510 @default.
- W2079653675 hasConceptScore W2079653675C126322002 @default.
- W2079653675 hasConceptScore W2079653675C134018914 @default.
- W2079653675 hasConceptScore W2079653675C15310415 @default.
- W2079653675 hasConceptScore W2079653675C185592680 @default.
- W2079653675 hasConceptScore W2079653675C2776719974 @default.
- W2079653675 hasConceptScore W2079653675C2777477808 @default.
- W2079653675 hasConceptScore W2079653675C2778311950 @default.
- W2079653675 hasConceptScore W2079653675C526171541 @default.
- W2079653675 hasConceptScore W2079653675C59377437 @default.
- W2079653675 hasConceptScore W2079653675C62231903 @default.
- W2079653675 hasConceptScore W2079653675C71924100 @default.
- W2079653675 hasConceptScore W2079653675C86803240 @default.
- W2079653675 hasIssue "2" @default.
- W2079653675 hasLocation W20796536751 @default.
- W2079653675 hasLocation W20796536752 @default.
- W2079653675 hasOpenAccess W2079653675 @default.
- W2079653675 hasPrimaryLocation W20796536751 @default.
- W2079653675 hasRelatedWork W2011373827 @default.
- W2079653675 hasRelatedWork W2021809084 @default.
- W2079653675 hasRelatedWork W2025567563 @default.
- W2079653675 hasRelatedWork W2032439565 @default.
- W2079653675 hasRelatedWork W2051982656 @default.
- W2079653675 hasRelatedWork W2068890132 @default.
- W2079653675 hasRelatedWork W2075320018 @default.
- W2079653675 hasRelatedWork W2088548547 @default.
- W2079653675 hasRelatedWork W2097554211 @default.
- W2079653675 hasRelatedWork W2132208960 @default.
- W2079653675 hasVolume "67" @default.
- W2079653675 isParatext "false" @default.
- W2079653675 isRetracted "false" @default.
- W2079653675 magId "2079653675" @default.
- W2079653675 workType "article" @default.