FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079654323> ?p ?o ?g. }

• W2079654323 endingPage "278" @default.
• W2079654323 startingPage "267" @default.
• W2079654323 abstract "This article reports the results of the analysis of the activation signals delivered to T and B cells by means of the CD44 molecule and an agonistic mAb, i.e., CB05 mAb, which is able to induce cell activation and aggregation upon binding. The functional effects culminate in T-cell proliferation in the presence of autologous accessory cells. Such effects are barely detectable in thymocytes, while B cells prove refractory to the action of the agonistic mAb. All of these events have been followed by the expression of surface activation markers, by the transcription of selected cytokine genes (IFN-γ, IL-4, and GM-CSF), and by the secretion of IL-2. Cell activation via CD44 has been evaluated as to its relationship with CD3 and CD2 activation pathways, proving synergistic with the latter. The CD44 signaling is protein kinase dependent, Furthermore, the role of surface molecules as cosignals in the CD44 pathway has been analyzed, showing that CD11a (and its ligand CD54), HLA class I, and CD25 are instrumental in the implementation of (a) efficient activation/proliferation signals and (b) a potent cytotoxic potential." @default.
• W2079654323 created "2016-06-24" @default.
• W2079654323 creator A5007447330 @default.
• W2079654323 creator A5009917845 @default.
• W2079654323 creator A5038497681 @default.
• W2079654323 creator A5070729253 @default.
• W2079654323 creator A5077639351 @default.
• W2079654323 date "1994-08-01" @default.
• W2079654323 modified "2023-10-18" @default.
• W2079654323 title "Stimulation of T cells via CD44 requires leukocyte-function-associated antigen interactions and interleukin-2 production" @default.
• W2079654323 cites W1479909263 @default.
• W2079654323 cites W1490812749 @default.
• W2079654323 cites W1515039418 @default.
• W2079654323 cites W1532739117 @default.
• W2079654323 cites W1533324377 @default.
• W2079654323 cites W1569428681 @default.
• W2079654323 cites W1575164560 @default.
• W2079654323 cites W1593480505 @default.
• W2079654323 cites W1966286149 @default.
• W2079654323 cites W1971589003 @default.
• W2079654323 cites W1978316761 @default.
• W2079654323 cites W1985006557 @default.
• W2079654323 cites W1985585224 @default.
• W2079654323 cites W1988019232 @default.
• W2079654323 cites W1992072758 @default.
• W2079654323 cites W2000517438 @default.
• W2079654323 cites W2001035036 @default.
• W2079654323 cites W2001605357 @default.
• W2079654323 cites W2005190805 @default.
• W2079654323 cites W2008323459 @default.
• W2079654323 cites W2010378504 @default.
• W2079654323 cites W2020455973 @default.
• W2079654323 cites W2023804521 @default.
• W2079654323 cites W2031742143 @default.
• W2079654323 cites W2071167287 @default.
• W2079654323 cites W2081120186 @default.
• W2079654323 cites W2088299703 @default.
• W2079654323 cites W2094657840 @default.
• W2079654323 cites W2102791307 @default.
• W2079654323 cites W2125572261 @default.
• W2079654323 cites W2132171625 @default.
• W2079654323 cites W2139838527 @default.
• W2079654323 cites W2160368254 @default.
• W2079654323 cites W2162535045 @default.
• W2079654323 cites W2259986819 @default.
• W2079654323 cites W4294216491 @default.
• W2079654323 doi "https://doi.org/10.1016/0198-8859(94)90026-4" @default.
• W2079654323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7528188" @default.
• W2079654323 hasPublicationYear "1994" @default.
• W2079654323 type Work @default.
• W2079654323 sameAs 2079654323 @default.
• W2079654323 citedByCount "29" @default.
• W2079654323 countsByYear W20796543232015 @default.
• W2079654323 countsByYear W20796543232016 @default.
• W2079654323 countsByYear W20796543232021 @default.
• W2079654323 countsByYear W20796543232022 @default.
• W2079654323 countsByYear W20796543232023 @default.
• W2079654323 crossrefType "journal-article" @default.
• W2079654323 hasAuthorship W2079654323A5007447330 @default.
• W2079654323 hasAuthorship W2079654323A5009917845 @default.
• W2079654323 hasAuthorship W2079654323A5038497681 @default.
• W2079654323 hasAuthorship W2079654323A5070729253 @default.
• W2079654323 hasAuthorship W2079654323A5077639351 @default.
• W2079654323 hasConcept C1491633281 @default.
• W2079654323 hasConcept C154317977 @default.
• W2079654323 hasConcept C185592680 @default.
• W2079654323 hasConcept C202751555 @default.
• W2079654323 hasConcept C203014093 @default.
• W2079654323 hasConcept C2776090121 @default.
• W2079654323 hasConcept C2778690821 @default.
• W2079654323 hasConcept C2780932548 @default.
• W2079654323 hasConcept C55493867 @default.
• W2079654323 hasConcept C79484868 @default.
• W2079654323 hasConcept C86803240 @default.
• W2079654323 hasConcept C8891405 @default.
• W2079654323 hasConcept C95444343 @default.
• W2079654323 hasConceptScore W2079654323C1491633281 @default.
• W2079654323 hasConceptScore W2079654323C154317977 @default.
• W2079654323 hasConceptScore W2079654323C185592680 @default.
• W2079654323 hasConceptScore W2079654323C202751555 @default.
• W2079654323 hasConceptScore W2079654323C203014093 @default.
• W2079654323 hasConceptScore W2079654323C2776090121 @default.
• W2079654323 hasConceptScore W2079654323C2778690821 @default.
• W2079654323 hasConceptScore W2079654323C2780932548 @default.
• W2079654323 hasConceptScore W2079654323C55493867 @default.
• W2079654323 hasConceptScore W2079654323C79484868 @default.
• W2079654323 hasConceptScore W2079654323C86803240 @default.
• W2079654323 hasConceptScore W2079654323C8891405 @default.
• W2079654323 hasConceptScore W2079654323C95444343 @default.
• W2079654323 hasIssue "4" @default.
• W2079654323 hasLocation W20796543231 @default.
• W2079654323 hasLocation W20796543232 @default.
• W2079654323 hasOpenAccess W2079654323 @default.
• W2079654323 hasPrimaryLocation W20796543231 @default.
• W2079654323 hasRelatedWork W1497833379 @default.
• W2079654323 hasRelatedWork W1964266791 @default.
• W2079654323 hasRelatedWork W2004466917 @default.
• W2079654323 hasRelatedWork W2040631670 @default.

• next