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- W2079654666 abstract "Abstract The influence of three orally administered beta-receptor blocking substances, propranolol (inhibiting both β 1 and β 2 -receptors), practolol (a β 1 -antagonist but with some sympathomimetic activity) and atenolol (solely a β 1 -receptor inhibitor devoid of sympathomimetic activity) on intraocular pressure (IOP) following repeated tonometry and episcleral venous pressure was investigated in healthy volunteers. The three beta-inhibitors caused a fall in mean IOP of both eyes which ranged from 1·5 to 3·5 mm Hg and was statistically significant with one exception. The reduction of IOP observed after repeated applanation tonometry was less pronounced during beta-adrenergic inhibition especially in the subjects treated with propranolol. Also terbutaline (a β 2 -adrenergic stimulator) caused a significant decrease in mean IOP (2·8−3·5 mmHg) and IOP fall induced by repeated applanation tonometry (one eye). No change of the episcleral venous pressure was observed during treatment with the four substances." @default.
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- W2079654666 date "1977-06-01" @default.
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- W2079654666 title "Effect of beta-adrenergic agonists and antagonists on repeated tonometry and episcleral venous pressure" @default.
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- W2079654666 doi "https://doi.org/10.1016/0014-4835(77)90119-1" @default.
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