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• W2079655215 abstract "Second-hand smoke (SHS) and tobacco smoke products (TSPs) are recognised global risks for human health. The present article reviews the causal role of SHS and TSPs for respiratory disorders in infants and young children. Several studies have shown an effect of TSPs exposure during pregnancy upon lung function in the newborn infant and of SHS on symptoms and lung function after birth. From 1997 to 1999 a set of systematic reviews concerning the relationship between second-hand exposure to tobacco smoke and respiratory health in children was published in Thorax by Cook and Strachan, covering hundreds of published papers. The evidence for a causal relationship between SHS exposure and asthmatic symptoms and reduced lung function is quite strong, whereas the evidence related to the development of allergy is much weaker. There is recent evidence relating to an interaction between TSP exposure and genetic ploymorphisms, demonstrating that certain individuals are more susceptible to the effect of TSP exposure on lung health. In the present review, an overview is given for the effects of TSP exposure and SHS upon lung health in children, with a focus on infants and young children. There is a need for intervention to reduce TSP exposure in young children, by educating parents and adolescents about the health effects of TSP exposure. Recent legislation in many European countries related to smoking in the workplace is of great importance for exposure during pregnancy. Studies are needed to identify possible critical periods for TSPs to induce harmful effects upon lung health in young children and on environment-gene interactions in order to prevent harm." @default.
• W2079655215 created "2016-06-24" @default.
• W2079655215 creator A5029186411 @default.
• W2079655215 creator A5078725957 @default.
• W2079655215 date "2008-03-01" @default.
• W2079655215 modified "2023-10-18" @default.
• W2079655215 title "Respiratory effects of tobacco smoking on infants and young children" @default.
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• W2079655215 doi "https://doi.org/10.1016/j.prrv.2007.11.007" @default.
• W2079655215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18280975" @default.
• W2079655215 hasPublicationYear "2008" @default.
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