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- W2079656338 endingPage "297" @default.
- W2079656338 startingPage "279" @default.
- W2079656338 abstract "Vascular endothelium plays a crucial role in ensuring normal function and morphology of blood vessels, and many risk factors of atherosclerosis act via their effects on endothelial cells. However, endothelial dysfunction is induced by very different pathomechanisms. In principle, it is caused by an impaired bioavailability of nitric oxide (NO) due to an inhibited synthesis (eg, by asymmetric dimethylarginine [ADMA]) or increased consumption of formed NO (by reactive oxygen species [ROS]). ROS can be synthesized in the organism (eg, by different enzymes) or can be administered from the environment (eg, by cigarette smoking), whereas ADMA is the subject of endogenous metabolism only. Many studies have elucidated the system of pathomechanisms and targeted some as potential goals for therapeutic interventions. This review demonstrates roles of ROS, NO, ADMA, endothelin, and estrogen in endothelial function and dysfunction focusing on homocysteinemia and diabetes mellitus and provide examples for the medical treatment of endothelial dysfunction." @default.
- W2079656338 created "2016-06-24" @default.
- W2079656338 creator A5000046286 @default.
- W2079656338 creator A5015339794 @default.
- W2079656338 creator A5058583705 @default.
- W2079656338 date "2008-08-05" @default.
- W2079656338 modified "2023-10-07" @default.
- W2079656338 title "Roles of Oxidants, Nitric Oxide, and Asymmetric Dimethylarginine in Endothelial Function" @default.
- W2079656338 cites W1492322138 @default.
- W2079656338 cites W1503255425 @default.
- W2079656338 cites W1582020189 @default.
- W2079656338 cites W180946569 @default.
- W2079656338 cites W1851010840 @default.
- W2079656338 cites W1860278769 @default.
- W2079656338 cites W1929253030 @default.
- W2079656338 cites W1951207992 @default.
- W2079656338 cites W1953477778 @default.
- W2079656338 cites W1964811030 @default.
- W2079656338 cites W1968813770 @default.
- W2079656338 cites W1975048966 @default.
- W2079656338 cites W1975199357 @default.
- W2079656338 cites W1975357252 @default.
- W2079656338 cites W1976555160 @default.
- W2079656338 cites W1983803438 @default.
- W2079656338 cites W1985498032 @default.
- W2079656338 cites W1985991573 @default.
- W2079656338 cites W1988349073 @default.
- W2079656338 cites W1991354189 @default.
- W2079656338 cites W1991883061 @default.
- W2079656338 cites W1992547254 @default.
- W2079656338 cites W1994394104 @default.
- W2079656338 cites W1995931698 @default.
- W2079656338 cites W2000796869 @default.
- W2079656338 cites W2003483877 @default.
- W2079656338 cites W2006197728 @default.
- W2079656338 cites W2007880055 @default.
- W2079656338 cites W2010866167 @default.
- W2079656338 cites W2016044148 @default.
- W2079656338 cites W2021836023 @default.
- W2079656338 cites W2022192502 @default.
- W2079656338 cites W2026425756 @default.
- W2079656338 cites W2026483758 @default.
- W2079656338 cites W2027627657 @default.
- W2079656338 cites W2031498851 @default.
- W2079656338 cites W2032874651 @default.
- W2079656338 cites W2033228105 @default.
- W2079656338 cites W2036313213 @default.
- W2079656338 cites W2037536867 @default.
- W2079656338 cites W2037655806 @default.
- W2079656338 cites W2037854429 @default.
- W2079656338 cites W2041661268 @default.
- W2079656338 cites W2041987907 @default.
- W2079656338 cites W2045773814 @default.
- W2079656338 cites W2050548878 @default.
- W2079656338 cites W2051043692 @default.
- W2079656338 cites W2051727048 @default.
- W2079656338 cites W2052055930 @default.
- W2079656338 cites W2053811269 @default.
- W2079656338 cites W2054194475 @default.
- W2079656338 cites W2055094699 @default.
- W2079656338 cites W2056338187 @default.
- W2079656338 cites W2061637057 @default.
- W2079656338 cites W2062023215 @default.
- W2079656338 cites W2063383552 @default.
- W2079656338 cites W2063784817 @default.
- W2079656338 cites W2064749533 @default.
- W2079656338 cites W2065501573 @default.
- W2079656338 cites W2066561068 @default.
- W2079656338 cites W2066688265 @default.
- W2079656338 cites W2066963386 @default.
- W2079656338 cites W2069077866 @default.
- W2079656338 cites W2073898414 @default.
- W2079656338 cites W2074334273 @default.
- W2079656338 cites W2076186944 @default.
- W2079656338 cites W2078981558 @default.
- W2079656338 cites W2081543748 @default.
- W2079656338 cites W2082517945 @default.
- W2079656338 cites W2083990676 @default.
- W2079656338 cites W2084445331 @default.
- W2079656338 cites W2084726391 @default.
- W2079656338 cites W2088204476 @default.
- W2079656338 cites W2089549133 @default.
- W2079656338 cites W2093518775 @default.
- W2079656338 cites W2096014264 @default.
- W2079656338 cites W2096127054 @default.
- W2079656338 cites W2097980836 @default.
- W2079656338 cites W2098154479 @default.
- W2079656338 cites W2098883620 @default.
- W2079656338 cites W2100342988 @default.
- W2079656338 cites W2102202839 @default.
- W2079656338 cites W2103709392 @default.
- W2079656338 cites W2104168812 @default.
- W2079656338 cites W2104630097 @default.
- W2079656338 cites W2105986115 @default.
- W2079656338 cites W2106478344 @default.
- W2079656338 cites W2107818859 @default.
- W2079656338 cites W2109698138 @default.
- W2079656338 cites W2110182057 @default.