Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079658245> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2079658245 endingPage "306" @default.
- W2079658245 startingPage "301" @default.
- W2079658245 abstract "Adhesion molecules play an important role in inflammatory reactions. Among them, ICAM1, a ligand for the lymphocyte function-associated antigen (FLA1) of leucocytes, may be expressed by antigen-presenting cells and keratinocytes in various inflammatory disorders. As cell-mediated immune responses play a great role in HPV infections, we investigated the expression of ICAM1 and correlated it with the presence of LFA1-positive cells by immunohistochemistry on serial frozen sections of a series of non-regressing cutaneous and mucosal HPV-induced lesions. ICAM1 expression by keratinocytes was observed only in intensely infiltrated lesions of condylomas and laryngeal papillomas. Its induction was usually correlated with the presence of LFA1-positive cells (mainly CD8-positive cells) which were in close apposition to ICAM1-positive proliferative epithelial cells expressing also, in some cases, HLA-DR antigen. ICAM1 was not correlated with the presence of HPV DNA or viral antigen. In moderately infiltrated lesions, keratinocytes did not express ICAM1, and LFA1-positive cells were not observed in the epidermis. In all lesions, ICAM1 was more intense on endothelial cells than in normal skin; infiltrating cells (lymphocytes and dendritic cells) may also express this antigen but intraepithelial Langerhans cells were devoid of any labelling. These studies provide further evidence that T-lymphocyte mechanisms are important in the host response to HPV-induced lesions. ICAM1 expression correlates with a lesional infiltrate but not with HPV infection and probably results in a more efficient initiation of the immune reaction." @default.
- W2079658245 created "2016-06-24" @default.
- W2079658245 creator A5027018058 @default.
- W2079658245 creator A5043730582 @default.
- W2079658245 creator A5053154374 @default.
- W2079658245 creator A5069193322 @default.
- W2079658245 date "1992-11-01" @default.
- W2079658245 modified "2023-10-03" @default.
- W2079658245 title "Epidermotropism of T cells correlates with intercellular adhesion molecule (ICAMI) expression in human papillomavirus (HPV)-induced lesions" @default.
- W2079658245 cites W1543214139 @default.
- W2079658245 cites W1965742429 @default.
- W2079658245 cites W1986105778 @default.
- W2079658245 cites W1995601990 @default.
- W2079658245 cites W1997255839 @default.
- W2079658245 cites W2017868450 @default.
- W2079658245 cites W2025280895 @default.
- W2079658245 cites W2029786286 @default.
- W2079658245 cites W2044065070 @default.
- W2079658245 cites W2051344486 @default.
- W2079658245 cites W2057616234 @default.
- W2079658245 cites W2063613980 @default.
- W2079658245 cites W2065692062 @default.
- W2079658245 cites W2073174286 @default.
- W2079658245 cites W2078880063 @default.
- W2079658245 cites W2088103643 @default.
- W2079658245 cites W2088425305 @default.
- W2079658245 cites W2112819617 @default.
- W2079658245 cites W2122334788 @default.
- W2079658245 cites W4240220715 @default.
- W2079658245 doi "https://doi.org/10.1002/path.1711680310" @default.
- W2079658245 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1361527" @default.
- W2079658245 hasPublicationYear "1992" @default.
- W2079658245 type Work @default.
- W2079658245 sameAs 2079658245 @default.
- W2079658245 citedByCount "11" @default.
- W2079658245 countsByYear W20796582452019 @default.
- W2079658245 crossrefType "journal-article" @default.
- W2079658245 hasAuthorship W2079658245A5027018058 @default.
- W2079658245 hasAuthorship W2079658245A5043730582 @default.
- W2079658245 hasAuthorship W2079658245A5053154374 @default.
- W2079658245 hasAuthorship W2079658245A5069193322 @default.
- W2079658245 hasConcept C105702510 @default.
- W2079658245 hasConcept C142724271 @default.
- W2079658245 hasConcept C147483822 @default.
- W2079658245 hasConcept C16224149 @default.
- W2079658245 hasConcept C167672396 @default.
- W2079658245 hasConcept C203014093 @default.
- W2079658245 hasConcept C204232928 @default.
- W2079658245 hasConcept C2776458125 @default.
- W2079658245 hasConcept C2777074287 @default.
- W2079658245 hasConcept C2777761686 @default.
- W2079658245 hasConcept C2909375385 @default.
- W2079658245 hasConcept C54355233 @default.
- W2079658245 hasConcept C71924100 @default.
- W2079658245 hasConcept C81885089 @default.
- W2079658245 hasConcept C86803240 @default.
- W2079658245 hasConcept C8891405 @default.
- W2079658245 hasConcept C95444343 @default.
- W2079658245 hasConceptScore W2079658245C105702510 @default.
- W2079658245 hasConceptScore W2079658245C142724271 @default.
- W2079658245 hasConceptScore W2079658245C147483822 @default.
- W2079658245 hasConceptScore W2079658245C16224149 @default.
- W2079658245 hasConceptScore W2079658245C167672396 @default.
- W2079658245 hasConceptScore W2079658245C203014093 @default.
- W2079658245 hasConceptScore W2079658245C204232928 @default.
- W2079658245 hasConceptScore W2079658245C2776458125 @default.
- W2079658245 hasConceptScore W2079658245C2777074287 @default.
- W2079658245 hasConceptScore W2079658245C2777761686 @default.
- W2079658245 hasConceptScore W2079658245C2909375385 @default.
- W2079658245 hasConceptScore W2079658245C54355233 @default.
- W2079658245 hasConceptScore W2079658245C71924100 @default.
- W2079658245 hasConceptScore W2079658245C81885089 @default.
- W2079658245 hasConceptScore W2079658245C86803240 @default.
- W2079658245 hasConceptScore W2079658245C8891405 @default.
- W2079658245 hasConceptScore W2079658245C95444343 @default.
- W2079658245 hasIssue "3" @default.
- W2079658245 hasLocation W20796582451 @default.
- W2079658245 hasLocation W20796582452 @default.
- W2079658245 hasOpenAccess W2079658245 @default.
- W2079658245 hasPrimaryLocation W20796582451 @default.
- W2079658245 hasRelatedWork W123978242 @default.
- W2079658245 hasRelatedWork W1995466872 @default.
- W2079658245 hasRelatedWork W1997255839 @default.
- W2079658245 hasRelatedWork W2010358369 @default.
- W2079658245 hasRelatedWork W2029474921 @default.
- W2079658245 hasRelatedWork W2132670907 @default.
- W2079658245 hasRelatedWork W2149871822 @default.
- W2079658245 hasRelatedWork W2334615195 @default.
- W2079658245 hasRelatedWork W2378619541 @default.
- W2079658245 hasRelatedWork W2409390451 @default.
- W2079658245 hasVolume "168" @default.
- W2079658245 isParatext "false" @default.
- W2079658245 isRetracted "false" @default.
- W2079658245 magId "2079658245" @default.
- W2079658245 workType "article" @default.