Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079659009> ?p ?o ?g. }
- W2079659009 endingPage "839" @default.
- W2079659009 startingPage "827" @default.
- W2079659009 abstract "Several recent studies suggested a role for neuronal major histocompatibility complex class I (MHCI) molecules in certain forms of synaptic plasticity in the hippocampus of rodents. Here, we report for the first time on the expression pattern and functional properties of MHCI molecules in the hippocampus of a nonhuman primate, the common marmoset monkey (Callithrix jacchus). We detected a presynaptic, mossy fiber-specific localization of MHCI proteins within the marmoset hippocampus. MHCI molecules were present in the large, VGlut1-positive, mossy fiber terminals, which provide input to CA3 pyramidal neurons. Furthermore, whole-cell recordings of CA3 pyramidal neurons in acute hippocampal slices of the common marmoset demonstrated that application of antibodies which specifically block MHCI proteins caused a significant decrease in the frequency, and a transient increase in the amplitude, of spontaneous excitatory postsynaptic currents (sEPSCs) in CA3 pyramidal neurons. These findings add to previous studies on neuronal MHCI molecules by describing their expression and localization in the primate hippocampus and by implicating them in plasticity-related processes at the mossy fiber–CA3 synapses. In addition, our results suggest significant interspecies differences in the localization of neuronal MHCI molecules in the hippocampus of mice and marmosets, as well as in their potential function in these species." @default.
- W2079659009 created "2016-06-24" @default.
- W2079659009 creator A5008709590 @default.
- W2079659009 creator A5023269476 @default.
- W2079659009 creator A5033883651 @default.
- W2079659009 creator A5036290198 @default.
- W2079659009 creator A5037214757 @default.
- W2079659009 creator A5048854580 @default.
- W2079659009 creator A5054567270 @default.
- W2079659009 creator A5070843451 @default.
- W2079659009 creator A5081516776 @default.
- W2079659009 date "2010-03-16" @default.
- W2079659009 modified "2023-10-15" @default.
- W2079659009 title "Neuronal MHC Class I Molecules are Involved in Excitatory Synaptic Transmission at the Hippocampal Mossy Fiber Synapses of Marmoset Monkeys" @default.
- W2079659009 cites W1564102226 @default.
- W2079659009 cites W1761352586 @default.
- W2079659009 cites W1920719136 @default.
- W2079659009 cites W1964372429 @default.
- W2079659009 cites W1967963204 @default.
- W2079659009 cites W1974897528 @default.
- W2079659009 cites W1981651297 @default.
- W2079659009 cites W1982988636 @default.
- W2079659009 cites W1988104458 @default.
- W2079659009 cites W1992586348 @default.
- W2079659009 cites W2001475468 @default.
- W2079659009 cites W2010003461 @default.
- W2079659009 cites W2018843440 @default.
- W2079659009 cites W2020634566 @default.
- W2079659009 cites W2023179463 @default.
- W2079659009 cites W2023967363 @default.
- W2079659009 cites W2025724570 @default.
- W2079659009 cites W2028160379 @default.
- W2079659009 cites W2030734894 @default.
- W2079659009 cites W2031319551 @default.
- W2079659009 cites W2040249614 @default.
- W2079659009 cites W2042962532 @default.
- W2079659009 cites W204348490 @default.
- W2079659009 cites W2047249162 @default.
- W2079659009 cites W2049389808 @default.
- W2079659009 cites W2058869509 @default.
- W2079659009 cites W2063781019 @default.
- W2079659009 cites W2064071741 @default.
- W2079659009 cites W2065786892 @default.
- W2079659009 cites W2073360590 @default.
- W2079659009 cites W2074655805 @default.
- W2079659009 cites W2076537666 @default.
- W2079659009 cites W2082405299 @default.
- W2079659009 cites W2082863207 @default.
- W2079659009 cites W2083928750 @default.
- W2079659009 cites W2084754989 @default.
- W2079659009 cites W2088016702 @default.
- W2079659009 cites W2093573816 @default.
- W2079659009 cites W2096472685 @default.
- W2079659009 cites W2104311488 @default.
- W2079659009 cites W2109987157 @default.
- W2079659009 cites W2112309752 @default.
- W2079659009 cites W2119809315 @default.
- W2079659009 cites W2137270049 @default.
- W2079659009 cites W2137422526 @default.
- W2079659009 cites W2159765217 @default.
- W2079659009 cites W2162452340 @default.
- W2079659009 cites W2166854598 @default.
- W2079659009 doi "https://doi.org/10.1007/s10571-010-9510-3" @default.
- W2079659009 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2912721" @default.
- W2079659009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20232136" @default.
- W2079659009 hasPublicationYear "2010" @default.
- W2079659009 type Work @default.
- W2079659009 sameAs 2079659009 @default.
- W2079659009 citedByCount "29" @default.
- W2079659009 countsByYear W20796590092012 @default.
- W2079659009 countsByYear W20796590092013 @default.
- W2079659009 countsByYear W20796590092014 @default.
- W2079659009 countsByYear W20796590092015 @default.
- W2079659009 countsByYear W20796590092017 @default.
- W2079659009 countsByYear W20796590092018 @default.
- W2079659009 countsByYear W20796590092019 @default.
- W2079659009 countsByYear W20796590092021 @default.
- W2079659009 countsByYear W20796590092023 @default.
- W2079659009 crossrefType "journal-article" @default.
- W2079659009 hasAuthorship W2079659009A5008709590 @default.
- W2079659009 hasAuthorship W2079659009A5023269476 @default.
- W2079659009 hasAuthorship W2079659009A5033883651 @default.
- W2079659009 hasAuthorship W2079659009A5036290198 @default.
- W2079659009 hasAuthorship W2079659009A5037214757 @default.
- W2079659009 hasAuthorship W2079659009A5048854580 @default.
- W2079659009 hasAuthorship W2079659009A5054567270 @default.
- W2079659009 hasAuthorship W2079659009A5070843451 @default.
- W2079659009 hasAuthorship W2079659009A5081516776 @default.
- W2079659009 hasBestOaLocation W20796590091 @default.
- W2079659009 hasConcept C112592302 @default.
- W2079659009 hasConcept C148762608 @default.
- W2079659009 hasConcept C151730666 @default.
- W2079659009 hasConcept C169760540 @default.
- W2079659009 hasConcept C170493617 @default.
- W2079659009 hasConcept C17077164 @default.
- W2079659009 hasConcept C200170125 @default.
- W2079659009 hasConcept C2776453536 @default.
- W2079659009 hasConcept C2776464000 @default.