Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079660047> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2079660047 abstract "The v-erbA oncogene has been discovered as one of the two viral oncogenes carried by the avian leukemia retrovirus AEV. It is derived from the c-erbA protooncogene which encodes the alpha form of the nuclear receptor for the thyroid hormone triiodothyronine (T3R). This receptor belongs to a large family of nuclear hormone receptors that function as ligand-regulated transcription factors and the v-erbA oncoprotein has been shown to function as an antagonist of normal T3R and related receptors in the control of transcription. It is thus the first dominant negative transcription factor acting as an oncogene described to date. Functional and biochemical dissections of this oncogene have brought many informations on the mechanisms of action of normal receptors and on the ways through which altered receptors can contribute to oncogenic transformation. The v-erbA model is widely used as a reference to investigate the involvement of nuclear hormone receptors in the development of human cancers." @default.
- W2079660047 created "2016-06-24" @default.
- W2079660047 creator A5019077858 @default.
- W2079660047 creator A5025041008 @default.
- W2079660047 creator A5089245484 @default.
- W2079660047 date "1995-01-01" @default.
- W2079660047 modified "2023-09-27" @default.
- W2079660047 title "THE V-ERBA ONCOGENE - A SUPERB TOOL FOR DISSECTING THE INVOLVEMENT OF NUCLEAR HORMONE RECEPTORS IN DIFFERENTIATION AND NEOPLASIA (REVIEW)" @default.
- W2079660047 doi "https://doi.org/10.3892/ijo.6.1.215" @default.
- W2079660047 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21556527" @default.
- W2079660047 hasPublicationYear "1995" @default.
- W2079660047 type Work @default.
- W2079660047 sameAs 2079660047 @default.
- W2079660047 citedByCount "4" @default.
- W2079660047 crossrefType "journal-article" @default.
- W2079660047 hasAuthorship W2079660047A5019077858 @default.
- W2079660047 hasAuthorship W2079660047A5025041008 @default.
- W2079660047 hasAuthorship W2079660047A5089245484 @default.
- W2079660047 hasConcept C104317684 @default.
- W2079660047 hasConcept C109115496 @default.
- W2079660047 hasConcept C121608353 @default.
- W2079660047 hasConcept C134018914 @default.
- W2079660047 hasConcept C1491633281 @default.
- W2079660047 hasConcept C149574134 @default.
- W2079660047 hasConcept C170493617 @default.
- W2079660047 hasConcept C23589133 @default.
- W2079660047 hasConcept C2781018059 @default.
- W2079660047 hasConcept C29537977 @default.
- W2079660047 hasConcept C502942594 @default.
- W2079660047 hasConcept C530470458 @default.
- W2079660047 hasConcept C54355233 @default.
- W2079660047 hasConcept C63932345 @default.
- W2079660047 hasConcept C71315377 @default.
- W2079660047 hasConcept C86339819 @default.
- W2079660047 hasConcept C86803240 @default.
- W2079660047 hasConcept C95444343 @default.
- W2079660047 hasConceptScore W2079660047C104317684 @default.
- W2079660047 hasConceptScore W2079660047C109115496 @default.
- W2079660047 hasConceptScore W2079660047C121608353 @default.
- W2079660047 hasConceptScore W2079660047C134018914 @default.
- W2079660047 hasConceptScore W2079660047C1491633281 @default.
- W2079660047 hasConceptScore W2079660047C149574134 @default.
- W2079660047 hasConceptScore W2079660047C170493617 @default.
- W2079660047 hasConceptScore W2079660047C23589133 @default.
- W2079660047 hasConceptScore W2079660047C2781018059 @default.
- W2079660047 hasConceptScore W2079660047C29537977 @default.
- W2079660047 hasConceptScore W2079660047C502942594 @default.
- W2079660047 hasConceptScore W2079660047C530470458 @default.
- W2079660047 hasConceptScore W2079660047C54355233 @default.
- W2079660047 hasConceptScore W2079660047C63932345 @default.
- W2079660047 hasConceptScore W2079660047C71315377 @default.
- W2079660047 hasConceptScore W2079660047C86339819 @default.
- W2079660047 hasConceptScore W2079660047C86803240 @default.
- W2079660047 hasConceptScore W2079660047C95444343 @default.
- W2079660047 hasLocation W20796600471 @default.
- W2079660047 hasLocation W20796600472 @default.
- W2079660047 hasOpenAccess W2079660047 @default.
- W2079660047 hasPrimaryLocation W20796600471 @default.
- W2079660047 hasRelatedWork W1989567929 @default.
- W2079660047 hasRelatedWork W2014482510 @default.
- W2079660047 hasRelatedWork W2063059112 @default.
- W2079660047 hasRelatedWork W2087368339 @default.
- W2079660047 hasRelatedWork W2114726210 @default.
- W2079660047 hasRelatedWork W2411435050 @default.
- W2079660047 hasRelatedWork W2491379183 @default.
- W2079660047 hasRelatedWork W3217698937 @default.
- W2079660047 hasRelatedWork W90907977 @default.
- W2079660047 hasRelatedWork W2187537356 @default.
- W2079660047 isParatext "false" @default.
- W2079660047 isRetracted "false" @default.
- W2079660047 magId "2079660047" @default.
- W2079660047 workType "article" @default.