FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079660114> ?p ?o ?g. }

• W2079660114 endingPage "8705" @default.
• W2079660114 startingPage "8701" @default.
• W2079660114 abstract "The nitrate reductase operon (narGHJI) of Escherichia coli encodes an anaerobic respiratory enzyme. Previous work has identified two cis-acting sites in the nar operon control region: a proximal site required for anaerobic induction mediated by the activator Fnr and a remote upstream site required for nitrate induction mediated by the activator NarL [Li, S. & DeMoss, J. A. (1988) J. Biol. Chem. 263, 13700-13705]. Our search for nar regulatory mutants yielded one strain with a mutation in himD, the structural gene for one of the subunits of integration host factor (IHF). Strains carrying null alleles of the IHF structural genes, himD and himA, had severe defects in nitrate induction of the nar operon but were normal for nitrate induction of the coordinately regulated fdn operon. Anaerobic expression of both operons was normal in him mutants. Gel-mobility-shift and DNase I protection experiments revealed a single IHF binding site in the nar operon control region, located midway between the upstream activation site and the promoter. We conclude that an IHF-mediated DNA bend is essential for efficient nitrate induction of the sigma 70-dependent nar operon promoter. This requirement of IHF for transcriptional activation had been noted for several sigma 54-dependent promoters." @default.
• W2079660114 created "2016-06-24" @default.
• W2079660114 creator A5000226146 @default.
• W2079660114 creator A5028641293 @default.
• W2079660114 creator A5036643594 @default.
• W2079660114 date "1992-09-15" @default.
• W2079660114 modified "2023-10-16" @default.
• W2079660114 title "In vivo requirement of integration host factor for nar (nitrate reductase) operon expression in Escherichia coli K-12." @default.
• W2079660114 cites W1017438797 @default.
• W2079660114 cites W1490370363 @default.
• W2079660114 cites W1534279694 @default.
• W2079660114 cites W1544705562 @default.
• W2079660114 cites W1548801077 @default.
• W2079660114 cites W1550600980 @default.
• W2079660114 cites W1554693762 @default.
• W2079660114 cites W1558516755 @default.
• W2079660114 cites W1558547246 @default.
• W2079660114 cites W1606902643 @default.
• W2079660114 cites W1609073127 @default.
• W2079660114 cites W1889088014 @default.
• W2079660114 cites W1894902271 @default.
• W2079660114 cites W1897119929 @default.
• W2079660114 cites W1930985780 @default.
• W2079660114 cites W1936991984 @default.
• W2079660114 cites W1938326461 @default.
• W2079660114 cites W1964713595 @default.
• W2079660114 cites W1970327774 @default.
• W2079660114 cites W1989080074 @default.
• W2079660114 cites W1997050091 @default.
• W2079660114 cites W1998975432 @default.
• W2079660114 cites W2004563262 @default.
• W2079660114 cites W2043268620 @default.
• W2079660114 cites W2050469077 @default.
• W2079660114 cites W2051449352 @default.
• W2079660114 cites W2061120858 @default.
• W2079660114 cites W2061467476 @default.
• W2079660114 cites W2061487060 @default.
• W2079660114 cites W2068658290 @default.
• W2079660114 cites W2076207892 @default.
• W2079660114 cites W2082927796 @default.
• W2079660114 cites W2087092102 @default.
• W2079660114 cites W2087782093 @default.
• W2079660114 cites W2088400016 @default.
• W2079660114 cites W2099105015 @default.
• W2079660114 cites W2100142020 @default.
• W2079660114 cites W2102626746 @default.
• W2079660114 cites W2104287309 @default.
• W2079660114 cites W2117859683 @default.
• W2079660114 cites W2130304914 @default.
• W2079660114 doi "https://doi.org/10.1073/pnas.89.18.8701" @default.
• W2079660114 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/49988" @default.
• W2079660114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1528882" @default.
• W2079660114 hasPublicationYear "1992" @default.
• W2079660114 type Work @default.
• W2079660114 sameAs 2079660114 @default.
• W2079660114 citedByCount "40" @default.
• W2079660114 countsByYear W20796601142014 @default.
• W2079660114 countsByYear W20796601142015 @default.
• W2079660114 countsByYear W20796601142017 @default.
• W2079660114 countsByYear W20796601142019 @default.
• W2079660114 crossrefType "journal-article" @default.
• W2079660114 hasAuthorship W2079660114A5000226146 @default.
• W2079660114 hasAuthorship W2079660114A5028641293 @default.
• W2079660114 hasAuthorship W2079660114A5036643594 @default.
• W2079660114 hasBestOaLocation W20796601141 @default.
• W2079660114 hasConcept C101762097 @default.
• W2079660114 hasConcept C104317684 @default.
• W2079660114 hasConcept C143065580 @default.
• W2079660114 hasConcept C150194340 @default.
• W2079660114 hasConcept C153911025 @default.
• W2079660114 hasConcept C181199279 @default.
• W2079660114 hasConcept C203075996 @default.
• W2079660114 hasConcept C2778710519 @default.
• W2079660114 hasConcept C54355233 @default.
• W2079660114 hasConcept C547475151 @default.
• W2079660114 hasConcept C55493867 @default.
• W2079660114 hasConcept C86803240 @default.
• W2079660114 hasConcept C88045685 @default.
• W2079660114 hasConceptScore W2079660114C101762097 @default.
• W2079660114 hasConceptScore W2079660114C104317684 @default.
• W2079660114 hasConceptScore W2079660114C143065580 @default.
• W2079660114 hasConceptScore W2079660114C150194340 @default.
• W2079660114 hasConceptScore W2079660114C153911025 @default.
• W2079660114 hasConceptScore W2079660114C181199279 @default.
• W2079660114 hasConceptScore W2079660114C203075996 @default.
• W2079660114 hasConceptScore W2079660114C2778710519 @default.
• W2079660114 hasConceptScore W2079660114C54355233 @default.
• W2079660114 hasConceptScore W2079660114C547475151 @default.
• W2079660114 hasConceptScore W2079660114C55493867 @default.
• W2079660114 hasConceptScore W2079660114C86803240 @default.
• W2079660114 hasConceptScore W2079660114C88045685 @default.
• W2079660114 hasIssue "18" @default.
• W2079660114 hasLocation W20796601141 @default.
• W2079660114 hasLocation W20796601142 @default.
• W2079660114 hasLocation W20796601143 @default.
• W2079660114 hasLocation W20796601144 @default.
• W2079660114 hasOpenAccess W2079660114 @default.
• W2079660114 hasPrimaryLocation W20796601141 @default.

• next