Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079662975> ?p ?o ?g. }
- W2079662975 endingPage "122" @default.
- W2079662975 startingPage "116" @default.
- W2079662975 abstract "To study the temporal nature of regional lung density changes and to assess whether the dose-dependent nature of these changes is associated with patient- and treatment-associated factors.Between 1991 and 2004, 118 patients with interpretable pre- and post-radiation therapy (RT) chest computed tomography (CT) scans were evaluated. Changes in regional lung density were related to regional dose to define a dose-response curve (DRC) for RT-induced lung injury using three-dimensional planning tools and image fusion. Multiple post-RT follow-up CT scans were evaluated by fitting linear-quadratic models of density changes on dose with time as the covariate. Various patient- and treatment-related factors were examined as well.There was a dose-dependent increase in regional lung density at nearly all post-RT follow-up intervals. The population volume-weighted changes evolved over the initial 6-month period after RT and reached a plateau thereafter (p < 0.001). On univariate analysis, patient age greater than 65 years (p = 0.003) and/or the use of pre-RT surgery (p < 0.001) were associated with significantly greater changes in CT density at both 6 and 12 months after RT, but the magnitude of this effect was modest.There appears to be a temporal nature for the dose-dependent increases in lung density. Nondosimetric clinical factors tend to have no, or a modest, impact on these changes." @default.
- W2079662975 created "2016-06-24" @default.
- W2079662975 creator A5000206324 @default.
- W2079662975 creator A5006664559 @default.
- W2079662975 creator A5016356279 @default.
- W2079662975 creator A5031650316 @default.
- W2079662975 creator A5060861535 @default.
- W2079662975 creator A5078538616 @default.
- W2079662975 creator A5082159241 @default.
- W2079662975 creator A5085651347 @default.
- W2079662975 creator A5085713638 @default.
- W2079662975 creator A5086702989 @default.
- W2079662975 date "2010-01-01" @default.
- W2079662975 modified "2023-10-12" @default.
- W2079662975 title "Regional Lung Density Changes After Radiation Therapy for Tumors in and Around Thorax" @default.
- W2079662975 cites W1907802084 @default.
- W2079662975 cites W1976732060 @default.
- W2079662975 cites W1979772891 @default.
- W2079662975 cites W1992893455 @default.
- W2079662975 cites W1997679487 @default.
- W2079662975 cites W2002108426 @default.
- W2079662975 cites W2002207094 @default.
- W2079662975 cites W2004921695 @default.
- W2079662975 cites W2005569659 @default.
- W2079662975 cites W2006693926 @default.
- W2079662975 cites W2022376122 @default.
- W2079662975 cites W2032142535 @default.
- W2079662975 cites W2033366141 @default.
- W2079662975 cites W2040296209 @default.
- W2079662975 cites W2051382622 @default.
- W2079662975 cites W2058000739 @default.
- W2079662975 cites W2060129596 @default.
- W2079662975 cites W2061076725 @default.
- W2079662975 cites W2086575048 @default.
- W2079662975 cites W2092718150 @default.
- W2079662975 cites W2098936813 @default.
- W2079662975 cites W2129216151 @default.
- W2079662975 cites W2139807361 @default.
- W2079662975 cites W2156199232 @default.
- W2079662975 cites W2166988903 @default.
- W2079662975 cites W2169190320 @default.
- W2079662975 doi "https://doi.org/10.1016/j.ijrobp.2009.01.025" @default.
- W2079662975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19406588" @default.
- W2079662975 hasPublicationYear "2010" @default.
- W2079662975 type Work @default.
- W2079662975 sameAs 2079662975 @default.
- W2079662975 citedByCount "47" @default.
- W2079662975 countsByYear W20796629752012 @default.
- W2079662975 countsByYear W20796629752013 @default.
- W2079662975 countsByYear W20796629752014 @default.
- W2079662975 countsByYear W20796629752015 @default.
- W2079662975 countsByYear W20796629752016 @default.
- W2079662975 countsByYear W20796629752017 @default.
- W2079662975 countsByYear W20796629752018 @default.
- W2079662975 countsByYear W20796629752019 @default.
- W2079662975 countsByYear W20796629752020 @default.
- W2079662975 countsByYear W20796629752021 @default.
- W2079662975 countsByYear W20796629752022 @default.
- W2079662975 countsByYear W20796629752023 @default.
- W2079662975 crossrefType "journal-article" @default.
- W2079662975 hasAuthorship W2079662975A5000206324 @default.
- W2079662975 hasAuthorship W2079662975A5006664559 @default.
- W2079662975 hasAuthorship W2079662975A5016356279 @default.
- W2079662975 hasAuthorship W2079662975A5031650316 @default.
- W2079662975 hasAuthorship W2079662975A5060861535 @default.
- W2079662975 hasAuthorship W2079662975A5078538616 @default.
- W2079662975 hasAuthorship W2079662975A5082159241 @default.
- W2079662975 hasAuthorship W2079662975A5085651347 @default.
- W2079662975 hasAuthorship W2079662975A5085713638 @default.
- W2079662975 hasAuthorship W2079662975A5086702989 @default.
- W2079662975 hasConcept C105702510 @default.
- W2079662975 hasConcept C126322002 @default.
- W2079662975 hasConcept C126838900 @default.
- W2079662975 hasConcept C187954543 @default.
- W2079662975 hasConcept C201645570 @default.
- W2079662975 hasConcept C2776256026 @default.
- W2079662975 hasConcept C2777714996 @default.
- W2079662975 hasConcept C2908647359 @default.
- W2079662975 hasConcept C2989005 @default.
- W2079662975 hasConcept C509974204 @default.
- W2079662975 hasConcept C544519230 @default.
- W2079662975 hasConcept C71924100 @default.
- W2079662975 hasConcept C97834683 @default.
- W2079662975 hasConcept C99454951 @default.
- W2079662975 hasConceptScore W2079662975C105702510 @default.
- W2079662975 hasConceptScore W2079662975C126322002 @default.
- W2079662975 hasConceptScore W2079662975C126838900 @default.
- W2079662975 hasConceptScore W2079662975C187954543 @default.
- W2079662975 hasConceptScore W2079662975C201645570 @default.
- W2079662975 hasConceptScore W2079662975C2776256026 @default.
- W2079662975 hasConceptScore W2079662975C2777714996 @default.
- W2079662975 hasConceptScore W2079662975C2908647359 @default.
- W2079662975 hasConceptScore W2079662975C2989005 @default.
- W2079662975 hasConceptScore W2079662975C509974204 @default.
- W2079662975 hasConceptScore W2079662975C544519230 @default.
- W2079662975 hasConceptScore W2079662975C71924100 @default.
- W2079662975 hasConceptScore W2079662975C97834683 @default.
- W2079662975 hasConceptScore W2079662975C99454951 @default.