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• W2079663388 abstract "Leukemic cells from 21 to 197 adult patients with de novo acute myelocytic leukemia (AML) were positive for IL-2R alpha chain (IL-2R alpha), whereas IL-2R beta chain (IL-2R beta), which is responsible for IL-2 signal transduction, was not found on leukemic cells from any of these cases tested. The expression of IL-2R alpha was closely associated with that of adhesion molecules CD4, CD11b and CD22, and endopeptidase CD10. None of the IL-2R alpha (+) AML cells responded to recombinant human IL-2. These data suggest that IL-2R alpha on AML cells may not be involved in cellular proliferation as one of growth factor receptors but may have a role in the control of cell-to-cell interactions." @default.
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• W2079663388 date "1993-01-01" @default.
• W2079663388 modified "2023-10-14" @default.
• W2079663388 title "Interleukin-2 receptor alpha chain on acute myelocytic leukemia cells is involved in cell-to-cell interactions" @default.
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• W2079663388 doi "https://doi.org/10.1016/0145-2126(93)90136-9" @default.
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