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• W2079667519 abstract "The ethanolic extract from stems of a Thai medicinal plant, Alstonia macrophylla Wall. ex G. Don (Apocynaceae) showed a significant inhibitory effect on acetylcholinesterase (AChE) determined by using Ellman assay. Four compounds i.e., a bisindole alkaloid, macralstonine (1), a new bisindole alkaloid, thungfaine (2), a secoiridoid glycoside, sweroside (3) and a new secoiridoid glycoside, naresuanoside (4) were isolated. Compound 4 showed moderate AChE and butyrylcholinesterase (BChE) inhibitory effects. Interestingly, compound 4 inhibited cell growth on human androgen-sensitive prostate cancer cell line (LNCaP) but no effect on viability of human foreskin fibroblast cells (HF)." @default.
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• W2079667519 date "2011-09-01" @default.
• W2079667519 modified "2023-10-03" @default.
• W2079667519 title "Bisindole alkaloids and secoiridoids from Alstonia macrophylla Wall. ex G. Don" @default.
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• W2079667519 doi "https://doi.org/10.1016/j.fitote.2011.04.013" @default.
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