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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079669030> ?p ?o ?g. }

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• W2079669030 abstract "We have reported that angiotensin II induces the epidermal growth factor (EGF) receptor transactivation leading to extracellular signal-regulated kinase (ERK) activation in rat vascular smooth muscle cells. Here, we report that the EGF receptor kinase inhibitor AG1478 and the ERK kinase inhibitor PD98059 markedly inhibited angiotensin II-induced c-Fos expression and protein synthesis but not c-Jun expression in these cells. These data suggest that the EGF receptor transactivation and subsequent ERK activation are indispensable for angiotensin II-mediated growth promotion of vascular smooth muscle cells providing a new mechanistic insight whereby angiotensin II contributes abnormal vascular remodeling." @default.
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• W2079669030 date "1999-07-01" @default.
• W2079669030 modified "2023-10-16" @default.
• W2079669030 title "Epidermal growth factor receptor is indispensable for c-Fos expression and protein synthesis by angiotensin II" @default.
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• W2079669030 doi "https://doi.org/10.1016/s0014-2999(99)00357-x" @default.
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