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• W2079671186 startingPage "783" @default.
• W2079671186 abstract "We have here, for the first time, used nanofabrication techniques to reproduce aspects of the ordered actomyosin arrangement in a muscle cell. The adsorption of functional heavy meromyosin (HMM) to five different resist polymers was first assessed. One group of resists (MRL-6000.1XP and ZEP-520) consistently exhibited high quality motility of actin filaments after incubation with HMM. A second group (PMMA-200, PMMA-950, and MRI-9030) generally gave low quality of motility with only few smoothly moving filaments. Based on these findings electron beam lithography was applied to a bi-layer resist system with PMMA-950 on top of MRL-6000.1XP. Grooves (100–200 nm wide) in the PMMA layer were created to expose the MRL-6000.1XP surface for adsorption of HMM and guidance of actin filament motility. This guidance was quite efficient allowing no U-turns of the filaments and approximately 20 times higher density of moving filaments in the grooves than on the surrounding PMMA." @default.
• W2079671186 created "2016-06-24" @default.
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• W2079671186 date "2003-02-01" @default.
• W2079671186 modified "2023-10-11" @default.
• W2079671186 title "Actomyosin motility on nanostructured surfaces" @default.
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• W2079671186 doi "https://doi.org/10.1016/s0006-291x(03)00027-5" @default.
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