Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079672766> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2079672766 endingPage "613" @default.
- W2079672766 startingPage "605" @default.
- W2079672766 abstract "A mouse monoclonal antibody (425/2B, IgM) was obtained which shows specificity for blood group M determinant of glycophorin A. The antibody is pH-dependent. At pH 6-7 it reacted strongly with blood group M antigen, but also cross-reacted distinctly with N antigen. At pH 8.3 the antibody showed moderately decreased reactivity with M antigen, but no interaction with N antigen was detectable by hemagglutination, immunoblotting, or microplate ELISA. The direct binding studies and inhibition of 425/B antibody by untreated or modified blood group M and N glycoproteins or tryptic glycopeptides showed that the binding to the antigens was not affected by acetylation of their amino groups, or removal of amino-terminal amino acid residue. Desialylation of the antigens decreased their reactivity with the antibody and this effect was distinctly stronger at pH 7 than 8.3. The antibody reacted strongly at pH 7 and 8.3 with glycophorin B of Henshaw phenotype, whereas its reactivity with normal glycophorin B was weak or undetectable at these pH values, respectively. The results obtained indicated that anti-M specificity of 425/2B antibody is related to the 5th amino acid residue of glycophorin A (anti-Mgly specificity) and that pH shift from 7 to 8.3 changes the fine specificity of the antibody. At pH 8.3 the reactivity of the antibody is more dependent on glycine residue (higher anti-M specificity) and less dependent on sialic acid residues in the antigen." @default.
- W2079672766 created "2016-06-24" @default.
- W2079672766 creator A5007450140 @default.
- W2079672766 creator A5049861616 @default.
- W2079672766 creator A5058006136 @default.
- W2079672766 creator A5072384428 @default.
- W2079672766 creator A5073067478 @default.
- W2079672766 date "1987-06-01" @default.
- W2079672766 modified "2023-10-04" @default.
- W2079672766 title "A monoclonal anti-glycophorin a antibody recognizing the blood group M determinant: Studies on the subspecificity" @default.
- W2079672766 cites W1497259627 @default.
- W2079672766 cites W1561943245 @default.
- W2079672766 cites W1589482850 @default.
- W2079672766 cites W184399086 @default.
- W2079672766 cites W1968834637 @default.
- W2079672766 cites W1971707709 @default.
- W2079672766 cites W1972353574 @default.
- W2079672766 cites W1996688922 @default.
- W2079672766 cites W2002624764 @default.
- W2079672766 cites W2027059080 @default.
- W2079672766 cites W2031593212 @default.
- W2079672766 cites W2033359280 @default.
- W2079672766 cites W2037620809 @default.
- W2079672766 cites W2050836523 @default.
- W2079672766 cites W2057086437 @default.
- W2079672766 cites W2087984384 @default.
- W2079672766 cites W2095352503 @default.
- W2079672766 cites W2096791417 @default.
- W2079672766 cites W2100837269 @default.
- W2079672766 cites W2114064011 @default.
- W2079672766 cites W2312355695 @default.
- W2079672766 cites W2319082472 @default.
- W2079672766 cites W2323124835 @default.
- W2079672766 cites W4249588969 @default.
- W2079672766 doi "https://doi.org/10.1016/0161-5890(87)90041-1" @default.
- W2079672766 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2443838" @default.
- W2079672766 hasPublicationYear "1987" @default.
- W2079672766 type Work @default.
- W2079672766 sameAs 2079672766 @default.
- W2079672766 citedByCount "67" @default.
- W2079672766 countsByYear W20796727662013 @default.
- W2079672766 countsByYear W20796727662014 @default.
- W2079672766 countsByYear W20796727662015 @default.
- W2079672766 countsByYear W20796727662022 @default.
- W2079672766 crossrefType "journal-article" @default.
- W2079672766 hasAuthorship W2079672766A5007450140 @default.
- W2079672766 hasAuthorship W2079672766A5049861616 @default.
- W2079672766 hasAuthorship W2079672766A5058006136 @default.
- W2079672766 hasAuthorship W2079672766A5072384428 @default.
- W2079672766 hasAuthorship W2079672766A5073067478 @default.
- W2079672766 hasConcept C108625454 @default.
- W2079672766 hasConcept C147483822 @default.
- W2079672766 hasConcept C153911025 @default.
- W2079672766 hasConcept C159654299 @default.
- W2079672766 hasConcept C185592680 @default.
- W2079672766 hasConcept C195616568 @default.
- W2079672766 hasConcept C203014093 @default.
- W2079672766 hasConcept C2780115458 @default.
- W2079672766 hasConcept C34343649 @default.
- W2079672766 hasConcept C542903549 @default.
- W2079672766 hasConcept C55493867 @default.
- W2079672766 hasConcept C67982717 @default.
- W2079672766 hasConcept C86803240 @default.
- W2079672766 hasConceptScore W2079672766C108625454 @default.
- W2079672766 hasConceptScore W2079672766C147483822 @default.
- W2079672766 hasConceptScore W2079672766C153911025 @default.
- W2079672766 hasConceptScore W2079672766C159654299 @default.
- W2079672766 hasConceptScore W2079672766C185592680 @default.
- W2079672766 hasConceptScore W2079672766C195616568 @default.
- W2079672766 hasConceptScore W2079672766C203014093 @default.
- W2079672766 hasConceptScore W2079672766C2780115458 @default.
- W2079672766 hasConceptScore W2079672766C34343649 @default.
- W2079672766 hasConceptScore W2079672766C542903549 @default.
- W2079672766 hasConceptScore W2079672766C55493867 @default.
- W2079672766 hasConceptScore W2079672766C67982717 @default.
- W2079672766 hasConceptScore W2079672766C86803240 @default.
- W2079672766 hasIssue "6" @default.
- W2079672766 hasLocation W20796727661 @default.
- W2079672766 hasLocation W20796727662 @default.
- W2079672766 hasOpenAccess W2079672766 @default.
- W2079672766 hasPrimaryLocation W20796727661 @default.
- W2079672766 hasRelatedWork W1604248381 @default.
- W2079672766 hasRelatedWork W1996802981 @default.
- W2079672766 hasRelatedWork W1997001434 @default.
- W2079672766 hasRelatedWork W2001280522 @default.
- W2079672766 hasRelatedWork W2068112600 @default.
- W2079672766 hasRelatedWork W2086697817 @default.
- W2079672766 hasRelatedWork W2364366187 @default.
- W2079672766 hasRelatedWork W347963503 @default.
- W2079672766 hasRelatedWork W4239344034 @default.
- W2079672766 hasRelatedWork W2024959369 @default.
- W2079672766 hasVolume "24" @default.
- W2079672766 isParatext "false" @default.
- W2079672766 isRetracted "false" @default.
- W2079672766 magId "2079672766" @default.
- W2079672766 workType "article" @default.