FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079672852> ?p ?o ?g. }

• W2079672852 endingPage "9" @default.
• W2079672852 startingPage "1" @default.
• W2079672852 abstract "When motoneuron axons in peripheral nerves are injured, the expression of the p75 low-affinity neurotrophin receptor (p75) increases in their cell bodies and axons, as well as in the Schwann cells undergoing Wallerian degeneration in the distal excised nerve segment. To understand the role of p75 in the events following nerve injury, we have examined the survival and regeneration of motoneurons in mice lacking the p75 receptor. In adult p75 (−/−) mice, functional recovery of whiskers movement following a facial nerve crush occurred slightly earlier than in p75 (+/+) mice, and some recovery of function over a 25-day interval following a nerve cut occurred more frequently in p75 (−/−) mice. Motoneuron profile numbers were slightly reduced in p75 (−/−) mice, and there were correspondingly fewer axons in the facial nerve. At 25 days following axotomy, profile survival in the adult p75 (−/−) mice was significantly improved compared to p75 (+/+) mice (mean 85% ± standard error of the mean 3%, n = 11 vs. 67 ± 5%, n = 11 in CD-1 mice and 68.0 ± 4%, n = 6 in balb/c mice), and significantly more regenerating axons were present in the distal facial nerve. After axotomy on postnatal day 1, there was almost total loss of motoneuron profiles in the lateral facial nucleus in p75 (+/+) mice (1.7 ± 0.3% remained, n = 5), while significantly more survived in p75 (−/−) mice (17 ± 2.5%, n = 6) . We conclude that expression of p75 in motoneurons or Schwann cells following facial nerve injury is not necessary for motoneuron survival or prompt regeneration of their axons; rather, p75 may increase their risk of dying. © 1998 John Wiley & Sons, Inc. J Neurobiol 34: 1–9, 1998" @default.
• W2079672852 created "2016-06-24" @default.
• W2079672852 creator A5033993630 @default.
• W2079672852 creator A5050099516 @default.
• W2079672852 creator A5076890958 @default.
• W2079672852 date "1998-01-01" @default.
• W2079672852 modified "2023-10-14" @default.
• W2079672852 title "Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor" @default.
• W2079672852 cites W1528648005 @default.
• W2079672852 cites W1898295630 @default.
• W2079672852 cites W1898813276 @default.
• W2079672852 cites W1966166748 @default.
• W2079672852 cites W1969808063 @default.
• W2079672852 cites W1984590320 @default.
• W2079672852 cites W1988624022 @default.
• W2079672852 cites W1992767896 @default.
• W2079672852 cites W1993995496 @default.
• W2079672852 cites W1996375432 @default.
• W2079672852 cites W1999972660 @default.
• W2079672852 cites W2011107311 @default.
• W2079672852 cites W2020397551 @default.
• W2079672852 cites W2022297536 @default.
• W2079672852 cites W2022951192 @default.
• W2079672852 cites W2030239560 @default.
• W2079672852 cites W2033255320 @default.
• W2079672852 cites W2034914242 @default.
• W2079672852 cites W2040397739 @default.
• W2079672852 cites W2050120071 @default.
• W2079672852 cites W2057458427 @default.
• W2079672852 cites W2059530040 @default.
• W2079672852 cites W2061050597 @default.
• W2079672852 cites W2061071594 @default.
• W2079672852 cites W2067642103 @default.
• W2079672852 cites W2069504770 @default.
• W2079672852 cites W2074369656 @default.
• W2079672852 cites W2093759370 @default.
• W2079672852 cites W2101821836 @default.
• W2079672852 cites W2113723285 @default.
• W2079672852 cites W2114216374 @default.
• W2079672852 cites W2134678910 @default.
• W2079672852 cites W2137547548 @default.
• W2079672852 cites W2142236496 @default.
• W2079672852 doi "https://doi.org/10.1002/(sici)1097-4695(199801)34:1<1::aid-neu1>3.0.co;2-c" @default.
• W2079672852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9469614" @default.
• W2079672852 hasPublicationYear "1998" @default.
• W2079672852 type Work @default.
• W2079672852 sameAs 2079672852 @default.
• W2079672852 citedByCount "127" @default.
• W2079672852 countsByYear W20796728522012 @default.
• W2079672852 countsByYear W20796728522013 @default.
• W2079672852 countsByYear W20796728522014 @default.
• W2079672852 countsByYear W20796728522015 @default.
• W2079672852 countsByYear W20796728522016 @default.
• W2079672852 countsByYear W20796728522017 @default.
• W2079672852 countsByYear W20796728522018 @default.
• W2079672852 countsByYear W20796728522019 @default.
• W2079672852 countsByYear W20796728522020 @default.
• W2079672852 countsByYear W20796728522021 @default.
• W2079672852 countsByYear W20796728522022 @default.
• W2079672852 countsByYear W20796728522023 @default.
• W2079672852 crossrefType "journal-article" @default.
• W2079672852 hasAuthorship W2079672852A5033993630 @default.
• W2079672852 hasAuthorship W2079672852A5050099516 @default.
• W2079672852 hasAuthorship W2079672852A5076890958 @default.
• W2079672852 hasConcept C105702510 @default.
• W2079672852 hasConcept C169760540 @default.
• W2079672852 hasConcept C170493617 @default.
• W2079672852 hasConcept C171056886 @default.
• W2079672852 hasConcept C2775991916 @default.
• W2079672852 hasConcept C2777004073 @default.
• W2079672852 hasConcept C2778423431 @default.
• W2079672852 hasConcept C2778987478 @default.
• W2079672852 hasConcept C2779683492 @default.
• W2079672852 hasConcept C2780862704 @default.
• W2079672852 hasConcept C55493867 @default.
• W2079672852 hasConcept C56703729 @default.
• W2079672852 hasConcept C86803240 @default.
• W2079672852 hasConcept C92020748 @default.
• W2079672852 hasConcept C95444343 @default.
• W2079672852 hasConceptScore W2079672852C105702510 @default.
• W2079672852 hasConceptScore W2079672852C169760540 @default.
• W2079672852 hasConceptScore W2079672852C170493617 @default.
• W2079672852 hasConceptScore W2079672852C171056886 @default.
• W2079672852 hasConceptScore W2079672852C2775991916 @default.
• W2079672852 hasConceptScore W2079672852C2777004073 @default.
• W2079672852 hasConceptScore W2079672852C2778423431 @default.
• W2079672852 hasConceptScore W2079672852C2778987478 @default.
• W2079672852 hasConceptScore W2079672852C2779683492 @default.
• W2079672852 hasConceptScore W2079672852C2780862704 @default.
• W2079672852 hasConceptScore W2079672852C55493867 @default.
• W2079672852 hasConceptScore W2079672852C56703729 @default.
• W2079672852 hasConceptScore W2079672852C86803240 @default.
• W2079672852 hasConceptScore W2079672852C92020748 @default.
• W2079672852 hasConceptScore W2079672852C95444343 @default.
• W2079672852 hasIssue "1" @default.
• W2079672852 hasLocation W20796728521 @default.
• W2079672852 hasLocation W20796728522 @default.
• W2079672852 hasOpenAccess W2079672852 @default.

• next