FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079674001> ?p ?o ?g. }

• W2079674001 endingPage "236" @default.
• W2079674001 startingPage "228" @default.
• W2079674001 abstract "We investigated the roles of the endothelium in the hypoxic responses of the isolated main pulmonary artery (PA) in the rat. Hypoxia was induced by gas-sing an organ chamber with 95% N2+5% CO2 (P02=34.6±3.1 Torr) instead of 16% O2+5% CO2+balance N2 (PO2=92.8±3.0 Torr). Vascular rings were precontracted with 2×10-8 M phenylephrine. A transient hypoxic contraction and a subsequent relaxation were observed in the endothelium-intact rings. The hypoxic contraction was reduced in the endothelium-denuded rings. In contrast, there were no significant differences between the hypoxic relaxation in the endothelium-intact and endothelium-denuded rings. Inhibitors of endothelium-derived relaxing factor (EDRF) activity, 2×10-6 M NG-monomethyl-L-arginine (L-NMMA) and 10-6 M methylene blue, produced 53% and 66% reductions in hypoxic contraction, respectively, Furthermore, the amount of cyclic GMP in the endothelium-intact PA rings which had been precontracted with phenylephrine decreased from 2. 10±0.45 pmol/mg protein during normoxia to 0.90±0.18 pmol/mg protein during hypoxia. Indomethacin and OKY-046 did not influence hypoxic contraction or relaxation. These results suggest that hypoxic contraction of the isolated pulmonary artery in the rat is partially induced by inhibition of the release of EDRF." @default.
• W2079674001 created "2016-06-24" @default.
• W2079674001 creator A5025914230 @default.
• W2079674001 creator A5028157595 @default.
• W2079674001 creator A5045329826 @default.
• W2079674001 creator A5065794411 @default.
• W2079674001 creator A5067227542 @default.
• W2079674001 creator A5078368687 @default.
• W2079674001 creator A5083562056 @default.
• W2079674001 creator A5089905179 @default.
• W2079674001 date "1993-01-01" @default.
• W2079674001 modified "2023-09-30" @default.
• W2079674001 title "Role of endothelium in biphasic hypoxic response of the isolated poumonary artery in the rat." @default.
• W2079674001 cites W1838917319 @default.
• W2079674001 cites W1842611921 @default.
• W2079674001 cites W1922132784 @default.
• W2079674001 cites W1973958247 @default.
• W2079674001 cites W1995272882 @default.
• W2079674001 cites W2004570632 @default.
• W2079674001 cites W2007737411 @default.
• W2079674001 cites W2015996189 @default.
• W2079674001 cites W2033851759 @default.
• W2079674001 cites W2053912690 @default.
• W2079674001 cites W2059174400 @default.
• W2079674001 cites W2068742980 @default.
• W2079674001 cites W2084121871 @default.
• W2079674001 cites W2090813942 @default.
• W2079674001 cites W2094489475 @default.
• W2079674001 cites W2096876364 @default.
• W2079674001 cites W2114355469 @default.
• W2079674001 cites W2117088919 @default.
• W2079674001 cites W2131957397 @default.
• W2079674001 cites W2162804111 @default.
• W2079674001 cites W2168104868 @default.
• W2079674001 cites W2169182236 @default.
• W2079674001 cites W2218997357 @default.
• W2079674001 cites W2258139430 @default.
• W2079674001 cites W2308198663 @default.
• W2079674001 cites W2398499060 @default.
• W2079674001 cites W2419968188 @default.
• W2079674001 doi "https://doi.org/10.1253/jcj.57.228" @default.
• W2079674001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8385231" @default.
• W2079674001 hasPublicationYear "1993" @default.
• W2079674001 type Work @default.
• W2079674001 sameAs 2079674001 @default.
• W2079674001 citedByCount "8" @default.
• W2079674001 countsByYear W20796740012012 @default.
• W2079674001 crossrefType "journal-article" @default.
• W2079674001 hasAuthorship W2079674001A5025914230 @default.
• W2079674001 hasAuthorship W2079674001A5028157595 @default.
• W2079674001 hasAuthorship W2079674001A5045329826 @default.
• W2079674001 hasAuthorship W2079674001A5065794411 @default.
• W2079674001 hasAuthorship W2079674001A5067227542 @default.
• W2079674001 hasAuthorship W2079674001A5078368687 @default.
• W2079674001 hasAuthorship W2079674001A5083562056 @default.
• W2079674001 hasAuthorship W2079674001A5089905179 @default.
• W2079674001 hasBestOaLocation W20796740011 @default.
• W2079674001 hasConcept C126322002 @default.
• W2079674001 hasConcept C134018914 @default.
• W2079674001 hasConcept C163415756 @default.
• W2079674001 hasConcept C178790620 @default.
• W2079674001 hasConcept C185592680 @default.
• W2079674001 hasConcept C2776992346 @default.
• W2079674001 hasConcept C2777952589 @default.
• W2079674001 hasConcept C2780310817 @default.
• W2079674001 hasConcept C2780940725 @default.
• W2079674001 hasConcept C42219234 @default.
• W2079674001 hasConcept C540031477 @default.
• W2079674001 hasConcept C71924100 @default.
• W2079674001 hasConcept C7836513 @default.
• W2079674001 hasConcept C84393581 @default.
• W2079674001 hasConceptScore W2079674001C126322002 @default.
• W2079674001 hasConceptScore W2079674001C134018914 @default.
• W2079674001 hasConceptScore W2079674001C163415756 @default.
• W2079674001 hasConceptScore W2079674001C178790620 @default.
• W2079674001 hasConceptScore W2079674001C185592680 @default.
• W2079674001 hasConceptScore W2079674001C2776992346 @default.
• W2079674001 hasConceptScore W2079674001C2777952589 @default.
• W2079674001 hasConceptScore W2079674001C2780310817 @default.
• W2079674001 hasConceptScore W2079674001C2780940725 @default.
• W2079674001 hasConceptScore W2079674001C42219234 @default.
• W2079674001 hasConceptScore W2079674001C540031477 @default.
• W2079674001 hasConceptScore W2079674001C71924100 @default.
• W2079674001 hasConceptScore W2079674001C7836513 @default.
• W2079674001 hasConceptScore W2079674001C84393581 @default.
• W2079674001 hasIssue "3" @default.
• W2079674001 hasLocation W20796740011 @default.
• W2079674001 hasLocation W20796740012 @default.
• W2079674001 hasOpenAccess W2079674001 @default.
• W2079674001 hasPrimaryLocation W20796740011 @default.
• W2079674001 hasRelatedWork W1966357256 @default.
• W2079674001 hasRelatedWork W1974488850 @default.
• W2079674001 hasRelatedWork W2026937065 @default.
• W2079674001 hasRelatedWork W2063786173 @default.
• W2079674001 hasRelatedWork W2079674001 @default.
• W2079674001 hasRelatedWork W2089799435 @default.
• W2079674001 hasRelatedWork W2129759033 @default.
• W2079674001 hasRelatedWork W2412835013 @default.

• next